Graefes Arch Clin Exp Ophthalmol:青光眼患者视网膜神经纤维层裂隙的长期随访结果

2018-07-10 cuiguizhong MedSci原创

台湾大学附属眼科医院眼科的Hsia Y等近日在Graefes Arch Clin Exp Ophthalmol发表了一篇文章,他们通过长期随访,调查了青光眼患者视网膜神经纤维层裂隙(RNFLCs)在结构和功能上的特征及变化。

台湾大学附属眼科医院眼科的Hsia Y等近日在Graefes Arch Clin Exp Ophthalmol发表了一篇文章,他们通过长期随访,调查了青光眼患者视网膜神经纤维层裂隙(RNFLCs)在结构和功能上的特征及变化。

这是一项回顾性纵向研究。30名受试者的43只眼中,在彩色眼底照相上检测到62个RNFLC位置。每6个月进行一次眼科检查、彩色眼底摄影、光学相干断层扫描(OCT)和视野(VF)测试,分析临床特征和切割区域结构和功能变化。

经过分析发现,RNFLC和局部玻璃体视网膜牵引最常发生在超颞叶视网膜血管旁。9个位置在OCT偏差图上有相应的缺陷,而31个位置与OCT偏差图上的缺陷相关。三个位置有相应的VF缺陷。与高度近视患者相比,更多的非高度近视患者有板层孔(p = 0.038)。青光眼患者的RNFLC病变在偏差图上与OCT缺陷存在相关性(p = 0.021)。眼部存在层板孔或RNFLCs数量在青光眼和非青光眼患者之间没有差异。在66.8±37.8个月的随访期间,分别由三名眼科医师独立对彩色眼底摄影、VF测试和OCT的GPA等结果进行分析,没有发现RNFLC在结构或功能有存在差异。RNFLC面积也没有统计学意义上的变化(p = 0.268)。

因此,他们认为,对早期青光眼患者经过长期随访后,未发现RNFLC在功能或结构上有显着的变化。

原文出处:

Hsia, Y., et al., Long-term follow-up of retinal nerve fiber layer cleavages in glaucoma patients and suspects. Graefes Arch Clin Exp Ophthalmol, 2018.

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    2019-03-12 amyloid
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    2018-07-12 zutt
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    2018-07-10 中医痴

    不错的.学习了.谢谢分享.

    0

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