Indian J Anaesth:危重患者并发热相关疾病的临床表现及转归

2017-07-28 MedSci MedSci原创

热相关疾病(HRI)是由于周围环境温度过高造成的一系列并发症,是印度夏季期间的常见病。中暑患者经常会因为症状严重而转入ICU进一步治疗,其发病率和死亡率也一直居高不下。然而,有关印度人群HRI影响的报道却一直少之又少。本研究旨在于确定热相关疾病患者的定义与ICU热相关患者的临床症状及其临床结局。

热相关疾病(HRI)是由于周围环境温度过高造成的一系列并发症,是印度夏季期间的常见病。中暑患者经常会因为症状严重而转入ICU进一步治疗,其发病率和死亡率也一直居高不下。然而,有关印度人群HRI影响的报道却一直少之又少。本研究旨在于确定热相关疾病患者的定义与ICU热相关患者的临床症状及其临床结局。

本研究对印度2012年夏天多个中心ICU发生热相关疾病的患者进行了回顾性病例研究。纳入研究的数据有:人口统计学资料、共同病态疾病、疾病严重程度(急性生理学和慢性健康评估Ⅱ【APACHE Ⅱ】)、器官衰竭评分(序贯器官衰竭评估【SOFA】)和神经影像学研究。研究结果包括死亡率、ICU住院天数、呼吸机使用时间和总住院天数。采用t检验、卡方检验和多元分析进行统计学分析。

对26例符合诊断标准的患者进行研究。其中15例男性,平均年龄53.12±18.6岁,平均APACHE Ⅱ评分为19.6±7.7,平均SOFA评分为7.5±2.6分。常见症状为发热伴神经损害(100%)和胃肠道症状(30%),主要器官系统受累包括神经系统(100%)、肾脏(57%)、肝脏(34%)和凝血功能异常(26%),最常见的代谢异常有低钠血症(73%)。其中26例患者中有5例表现为中暑,总死亡率为34%,17名幸存者中8人有残余神经损伤。

所以,热相关疾病患者的发病率和死亡率非常高,而且通常会合并明显的神经系统损伤。

原始出处:

Kalaiselvan MS1, Renuka MK2,  et al. A retrospective study of clinical profile and outcomes of critically ill patients with heat-related illness. Indian J Anaesth. 2015 Nov;59(11):715-20. doi: 10.4103/0019-5049.170030.

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    2017-12-15 AspirantSuo
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level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Jul 29 06:47:23 CST 2017, time=2017-07-29, status=1, ipAttribution=)]
    2017-07-31 txqjm

    谢谢了,学习

    0

  6. 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level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Jul 29 06:47:23 CST 2017, time=2017-07-29, status=1, ipAttribution=)]
    2017-07-30 xiaogang319
  7. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Jul 29 08:05:48 CST 2017, time=2017-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227539, encodeId=d06122e53943, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Jul 29 07:35:16 CST 2017, time=2017-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227509, encodeId=a65f22e5099d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Jul 29 06:47:23 CST 2017, time=2017-07-29, status=1, ipAttribution=)]
    2017-07-29 天涯183

    非常好的文章,学习了,很受益

    0

  8. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Jul 29 08:05:48 CST 2017, time=2017-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227539, encodeId=d06122e53943, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Jul 29 07:35:16 CST 2017, time=2017-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227509, encodeId=a65f22e5099d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Jul 29 06:47:23 CST 2017, time=2017-07-29, status=1, ipAttribution=)]
    2017-07-29 惠映实验室

    学习了,谢谢

    0

  9. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sat Jul 29 08:05:48 CST 2017, time=2017-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227539, encodeId=d06122e53943, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sat Jul 29 07:35:16 CST 2017, time=2017-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=227509, encodeId=a65f22e5099d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Jul 29 06:47:23 CST 2017, time=2017-07-29, status=1, ipAttribution=)]
    2017-07-29 龙胆草

    学习谢谢分享

    0

  10. 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level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo5nmIH5IQqCKjJgSCuicPWUWOUcdqt1ROPnEiaOYN4pSHibDv8la3OxNLalvuvUXn8clpJlrpuyTpckgt9OPkeSSdT/0, createdBy=8fd71930726, createdName=半夏微凉, createdTime=Sat Jul 29 06:47:23 CST 2017, time=2017-07-29, status=1, ipAttribution=)]
    2017-07-29 半夏微凉

    学习了谢谢分享

    0