BMC Pulm Med:过去20年哮喘、鼻炎和呼吸系统症状流行度变化

2018-10-05 AlexYang MedSci原创

最近,有研究人员调查了过去20年成年人中呼吸道症状和障碍以及与之相关的出生时间、生活方式和睡眠相关变量的变化情况。研究包括了6085名女性和5184名男性,年龄在20-44岁之间,他们随机选自北欧7个中心,并且跟踪调查了20年。参与第一次调查的参与者数量达到了21595名,并且11269名参与了所有的3项调查。参与者被分成了3个出生年龄段:1944-1955, 1956-1965和1966-197

最近,有研究人员调查了过去20年成年人中呼吸道症状和障碍以及与之相关的出生时间、生活方式和睡眠相关变量的变化情况。研究包括了6085名女性和5184名男性,年龄在20-44岁之间,他们随机选自北欧7个中心,并且跟踪调查了20年。参与第一次调查的参与者数量达到了21595名,并且11269名参与了所有的3项调查。参与者被分成了3个出生年龄段:1944-1955, 1956-1965和1966-1975。

研究发现,在20年时间里,喘息的流行度减少(-2%)、哮喘和过敏性鼻炎的流行度上升(+4%和+5%),然而,夜间呼吸症状流行度没有变化。在1966和1975年出生组中,过敏性鼻炎的增加幅度最大,不包括爱沙尼亚。在研究期间,抽烟的减少(-20%)、肥胖的增加(+7%)和打鼾(+6%)变化幅度较大。抽烟、肥胖、打鼾和夜间食道逆流(nGER)与所有症状更高的风险相关。肥胖、打鼾和nGER与哮喘无相关性。

最后,研究人员指出,随着他们研究群体年龄变大,喘息减少,夜间症状没有变化,并且报道的哮喘和过敏性鼻炎增加。这些变化可能与抽烟的减少有关,但是同样被过敏、肥胖和睡眠相关障碍抵消。

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    2018-11-17 13718711b3m

    非常不错的学习资料,学习了,值得借鉴的临床经验,获益匪浅,感谢分享!

    0

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    2018-10-08 13718711b3m

    非常好的临床经验,学习了,受益匪浅,涨见识,谢谢分享!

    0

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Clin Exp Allergy:6岁时候的非特应性鼻炎与随后哮喘的发展相关

之前,有研究人员假设过敏性鼻炎与哮喘的相关性可以归结到儿童时期呼吸道炎症的持续临床表现。早期非过敏性鼻炎与哮喘的关系仍旧没有很好的研究。最近,有研究人员进行了旨在确定是否早期的鼻炎与成年时候的哮喘的风险相关,以及是否该相关性与过敏无关。研究总共有521名参与者符合入选要求。与非特应性非鼻炎组相比,在调整了性别、种族、母亲肖传、母亲教育和抽烟以及6岁时不少于4次感冒历史后,非特应性鼻炎患者在8岁到3

BORA III期延展试验证明阿斯利康IL-5单抗Fasenra对严重哮喘具有长期疗效

阿斯利康近日公布了BORA III期延展试验的数据,该试验证明了Fasenra(benralizumab)对严重嗜酸性粒细胞性哮喘患者的辅助维持治疗的功效。