Clin Gastroenterology H:胃轻瘫到底与什么有关?

2019-07-14 不详 MedSci原创

胃轻瘫是一种慢性胃病,其特征为恶心,呕吐,早饱,餐后饱胀和腹痛。本项研究评估了胃轻瘫患者的病因,症状,生活质量,胃排空,治疗和症状结果的在不同种族和性别中的差异。

背景与目的
轻瘫是一种慢性病,其特征为恶心,呕吐,早饱,餐后饱胀和腹痛。本项研究评估了胃轻瘫患者的病因,症状,生活质量,胃排空,治疗和症状结果的在不同种族和性别中的差异。

方法
研究人员收集了2007年9月至2017年12月间美国国立卫生研究院胃病患者协会的718名成年患者的临床资料。每4或6个月对患者进行一次随访,收集有关病史,症状的数据和生活质量(基于SF-36量表)。最后研究人员对自我报告的非西班牙裔白人,非西班牙裔黑人和西班牙裔人以及男性和女性患者之间的患者进行了比较。

结果

本项研究共纳入552名非西班牙裔白人(77%),83名西班牙裔(12%),62名非西班牙裔黑人(9%),其中603名女性(84%),115名男性(16%)。胃轻瘫患者中非西班牙裔黑人(60%)患糖尿病的比例明显高于非西班牙裔白人(28%); 非西班牙裔黑人也有更严重的干呕(2.5% VS 1.7%)和呕吐(2.9% VS 1.8%),并且在过去一年住院的比例更高(66% VS 38%)。西班牙裔糖尿病患者胃轻瘫的比例(59%)明显高于非西班牙裔白人(28%),但西班牙裔患者的恶心程度较轻(2.7% vs 3.3%),早期饱腹感较少(3.0% vs 3.5%分),使用多潘立酮的比例较低(8% vs 21%)或外周插入中心导管(1%vs 7%)。女性特发性病因胃轻瘫(69%)的比例高于男性(46%); 女性胃部饱胀症状较严重(3.6% vs 3.1%),早饱(3.5% vs 2.9%),餐后饱满(3.7% vs 3.1%),腹胀(3.3% vs 2.6%),胃明显增大(3.0% vs 2.1%)和上腹部疼痛(2.9% vs 2.4%)。

结论
对于胃轻瘫患者,病因,症状严重程度和治疗方法因种族和民族以及性别而有差异。

原始出处:

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    2019-10-13 许安
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