Am Heart J:间歇性跛行患者进行监护锻炼更能提高很大步行距离和跛行距离

2015-06-10 张旭栋译 MedSci原创

背景:间歇性跛行(IC)患者进行监护锻炼(SE)作为一种有效的治疗手段被广泛接受,但它的使用却受到成本的限制。患者进行无监督训练(UE)成本更低。本研究评估了间歇性跛行的患者SE和 UE的疗效差别。 方法和结果:研究检索了PubMed,EMBAS,和Cochrane系统评价数据库,并确定了27独特的研究(24项随机对照试验,4观察性研究),选取了2074例间歇性跛行患者,对SE患者和UE患者的

背景:间歇性跛行(IC)患者进行监护锻炼(SE)作为一种有效的治疗手段被广泛接受,但它的使用却受到成本的限制。患者进行无监督训练(UE)成本更低。本研究评估了间歇性跛行的患者SE和 UE的疗效差别。

方法和结果:研究检索了PubMed,EMBAS,和Cochrane系统评价数据库,并确定了27独特的研究(24项随机对照试验,4观察性研究),选取了2074例间歇性跛行患者,对SE患者和UE患者的疗效做了比较。与UE患者相比,SE患者最大步行距离分别在6个月和12个月时有了改善,分别是6个月:效应值0.77,95%可信区间为0.36至1.17,P <0.001;12个月:效应值:0.56,95%可信区间为0.34至0.77, P <0.001。与UE患者相比,SE患者跛行距离在6个月和12个月时也有了改善,分别是6个月:效应值0.63,95%可信区间0.40至0.85,P <0.001;12个月效应值0.41,95%可信区间0.18至0.65,P= 0.001。6个月时,生活质量评价量表SF36(效应值-0.05,95%可信区间-0.50至0.41,P=0.84),行走受损问卷(效应值0.24,95%可信区间-0.03至.50,P=0.08)和行走速度(效应值0.26,95%可信区间-0.06至0.59,P=0.11)并没有显著差异。

结局:间歇性跛行患者中,在提高最大步行距离和跛行距离上,SE比UE更有效果,但在生活质量、社区为基础的步行量上却没有差异。功能恢复和疾病特异性生活质量的关系仍需要进一步的研究。

原文出处:

Vemulapalli S, Dolor RJ, Hasselblad V, Schmit K, Banks A, Heidenfelder B, Patel MR, Jones WS. Supervised vs unsupervised exercise for intermittent claudication: A systematic review and meta-analysis. American heart journal. 2015;169(6):924-37.e3.

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    2016-03-02 yuanming15
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    2015-09-09 Bobby7868

    间歇性跛行很影响生活治疗,本文有用

    0

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    2015-06-12 zhaojie88
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    2015-06-12 bioon6
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    2015-06-12 slcumt

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