Am J Gastroenterol:季节因素对粪便免疫化学试验性能的影响

2018-03-09 zhangfan MedSci原创

研究发现,粪便免疫化学试验的检出性能存在季节差异,夏季粪便免疫化学试验阳性率最低。夏季时,肠道肿瘤高危人群的筛查最具预测价值

近日韩国研究人员利用国家癌症结直肠癌筛查结果资料,探讨了气候的季节性变化对粪便免疫化学试验性能(FIT)的影响。

参与者于2009-10年间接受FIT筛查,研究人员比较一年四季中FIT筛查阳性率、肿瘤检出率、间隔期肿瘤率、阳性预测价值、敏感性和特异性差异。

总计4788104个FIT样本参与分析,研究发现,夏季FIT阳性率在一年中最低。统计发现,夏季FIT的阳性预测价值较其他季节高1.1-1.3倍。肿瘤检出率不受季节影响,夏季患者间隔期肿瘤检出率较其他季节提高1.16-1.31倍。此外,研究人员发现对于直肠和远端结肠间隔期肿瘤的检出率,夏秋季最高,其次是冬季。

研究发现,粪便免疫化学试验的检出性能存在季节差异,夏季粪便免疫化学试验阳性率最低。夏季时,肠道肿瘤高危人群的筛查最具预测价值。

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    2018-03-15 虈亣靌

    了解一下.谢谢分享!

    0

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    2018-03-11 Homburg
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    2018-03-11 30397606
  8. [GetPortalCommentsPageByObjectIdResponse(id=2072097, encodeId=1f3020e2097f5, content=<a href='/topic/show?id=9d4ee84647' target=_blank style='color:#2F92EE;'>#GAS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7846, encryptionId=9d4ee84647, topicName=GAS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e2dd327, createdName=许安, createdTime=Wed May 09 23:43:00 CST 2018, time=2018-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1772880, encodeId=82531e7288017, content=<a href='/topic/show?id=d7e1e6312cd' target=_blank style='color:#2F92EE;'>#粪便免疫化学试验#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76312, encryptionId=d7e1e6312cd, topicName=粪便免疫化学试验)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=87e738436293, createdName=makuansheng, createdTime=Mon Dec 24 13:43:00 CST 2018, time=2018-12-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1711409, encodeId=f92f1e11409cf, content=<a href='/topic/show?id=9a1c289680' target=_blank style='color:#2F92EE;'>#AST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2896, encryptionId=9a1c289680, topicName=AST)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b9831894722, createdName=ms24272190615788285182, createdTime=Fri Jan 18 12:43:00 CST 2019, time=2019-01-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2064335, encodeId=fb772064335b1, content=<a href='/topic/show?id=94ffe853a7' target=_blank style='color:#2F92EE;'>#Gastroenterol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7853, encryptionId=94ffe853a7, topicName=Gastroenterol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0bed488, createdName=jktdtl, createdTime=Wed May 30 08:43:00 CST 2018, time=2018-05-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=296447, encodeId=2e6529644e26, content=了解一下.谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Thu Mar 15 10:11:14 CST 2018, time=2018-03-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1466819, encodeId=49c5146681903, content=<a href='/topic/show?id=edd5e630426' target=_blank style='color:#2F92EE;'>#粪便#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76304, encryptionId=edd5e630426, topicName=粪便)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=03cc6863823, createdName=Homburg, createdTime=Sun Mar 11 00:43:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1468682, encodeId=772814686822e, content=<a href='/topic/show?id=a19b4540688' target=_blank style='color:#2F92EE;'>#季节#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=45406, encryptionId=a19b4540688, topicName=季节)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cf986929326, createdName=30397606, createdTime=Sun Mar 11 00:43:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294505, encodeId=33c729450500, content=好好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Fri Mar 09 10:58:03 CST 2018, time=2018-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294494, encodeId=a8cf294494b1, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Fri Mar 09 10:17:52 CST 2018, time=2018-03-09, status=1, ipAttribution=)]
    2018-03-09 139****5926

    好好文章学习了

    0

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    2018-03-09 1ddf0692m34(暂无匿称)

    学习了.谢谢分享

    0

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