J Am Coll Cardiol:60分钟内给速尿,院内死亡降61%

2017-07-11 许菁 中国循环杂志

日本REALITY-AHF前瞻性研究显示,对于急性心衰患者,1小时内静射速尿,可使院内死亡率降低61%。

日本REALITY-AHF前瞻性研究显示,对于急性心衰患者,1小时内静射速尿,可使院内死亡率降低61%。

研究者定义从就诊到速尿给药时间是指患者到达急诊的时间至首次静注速尿的时间(D2F)。

本研究中,就诊后24小时内静注速尿的1291例急性心衰患者中,中位D2F时间为90分钟,仅37%患者在就诊60分钟内应用了速尿。这类患者多是通过救护车到达医院,而且多有更明显的充血症状。

数据显示,就诊60分钟内应用了速尿患者的院内死亡率显着低于60分钟后应用速尿的患者(2.3% vs. 6.0%)。

进一步分析显示,就诊60分钟内应用速尿可使院内死亡率降低61%。

研究者还发现,在到达急诊的前几个小时内,死亡率会随着D2F时间的延迟而快速升高,但在100分钟时两者的关系趋于平稳。

原始出处:

Matsue Y, Damman K, Voors AA, et al. Time-to-Furosemide Treatment and Mortality in Patients Hospitalized With Acute Heart Failure. J Am Coll Cardiol, 2017, 69: 3042-3051.

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    2017-09-18 waiwai3030
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    2017-07-12 王秀

    学习了,涨知识了!

    0

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    2017-07-11 131****1460

    学习了受益匪浅。

    0

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