Pirbright研究所证明,两剂ChAdOx1 nCoV-19(AZD1222)疫苗可增强猪的免疫反应

2020-06-24 Allan MedSci原创

在猪中,两剂ChAdOx1 nCoV-19(AZD1222)疫苗产生的抗体反应要大于单剂。

COVID-19的全球性大流行继续对人类健康以及世界经济产生着巨大影响。迫切需要疫苗来预防COVID-19并减少SARS-CoV-2的传播,以应对这种全球紧急情况。

ChAdOx1 nCoV-19(AZD1222)疫苗由牛津大学研发,是一种黑猩猩腺病毒载体疫苗,其中含有表达SARS-CoV-2的刺突蛋白的基因。一项研究显示,猕猴在经AZD1222单次免疫后可以预防肺部疾病,因此已经开始进行单剂量疫苗的I期人体临床试验。

与牛津大学合作的Pirbright研究所已成功地证明,在猪中,两剂ChAdOx1 nCoV-19(AZD1222)疫苗产生的抗体反应要大于单剂。在Pirbright进行的研究旨在确定在猪中接种两剂疫苗(初次和加强免疫)是否可能引起更大的免疫反应。结果表明,两剂ChAdOx1 nCoV-19疫苗在猪中引起明显更大的抗体反应。研究人员发现中和抗体水平显著增加,该中和抗体以阻断感染的方式与病毒结合。

 

原始出处:

https://www.firstwordpharma.com/node/1734877?tsid=4

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    2020-06-26 muzishouyi
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    2020-06-24 lovetcm

    #新冠肺炎#AZ开发的疫苗

    0

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    2020-06-24 lovetcm

    阿斯利康开发的新冠疫苗#阿斯利康#

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