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Gut：各期胃炎患者癌变风险评估

2018-01-08 zhangfan MedSci原创

胃癌胃炎OLGA
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研究再次确证了可操作的与胃癌风险联系的胃炎评估对胃上皮瘤风险的预测效果，幽门螺杆菌清除后III-IV期胃炎患者的肿瘤进展风险增加

可操作的与胃癌风险联系的胃炎评估(OLGA)可有效评估各期胃炎(0-IV)的癌变风险。近日研究人员开展前瞻性研究考察各期胃炎患者的肿瘤风险。

1755名因消化不良就诊患者接受初始(T-0)胃活检、食管胃十二指肠镜、OLGA以及幽门螺杆菌检查。平均随访55个月， II-IV期胃炎患者接受二次内镜/再狭窄检查(T-1)。研究的主要终点是T1患者OLGA状态以及胃上皮瘤发展。

T-0期，77.6%的患者处于胃炎0阶段，14.4%的患者处于I期，5.1%的患者处于II期，2.1%的患者处于III期，0.85%的患者处于IV期；603名患者幽门螺杆菌阳性，其中602人成功根除。220人有幽门螺杆菌阳性根除史，932人阴性。III-IV期胃炎患者，侵袭性肿瘤发病率为0.4%，低度上皮内瘤变患者4人，高度上皮内瘤变1人，胃癌2人。0-II期胃炎患者上皮内瘤变风险为0，III期患者为每1000患者年36.5，IV期患者为每1000患者年63.1。

研究再次确证了可操作的与胃癌风险联系的胃炎评估对胃上皮瘤风险的预测效果，幽门螺杆菌清除后III-IV期胃炎患者的肿瘤进展风险增加。

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    2018-01-10 axin014

    #癌变#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1557064, encodeId=26db155e06412, content=<a href='/topic/show?id=154be128170' target=_blank style='color:#2F92EE;'>#癌变#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71281, encryptionId=154be128170, topicName=癌变)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cd7914850828, createdName=axin014, createdTime=Wed Jan 10 00:09:00 CST 2018, time=2018-01-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276919, encodeId=f1232e691985, content=好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Tue Jan 09 16:31:02 CST 2018, time=2018-01-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276725, encodeId=8bc72e67257a, content=0-II期胃炎患者上皮内瘤变风险为0.III期患者为每1000患者年36.5.IV期患者为每1000患者年63.1., beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Mon Jan 08 23:31:00 CST 2018, time=2018-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276617, encodeId=d2b52e661761, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJpBl6xwMmnsKibwxcAIltOH3nnCEQbNE6TDbYtCKe8hYI0oJrbduNqnJraM1PyyjPKU1suAzicYPaA/132, createdBy=eeaf2031798, createdName=海之蓝, createdTime=Mon Jan 08 14:07:17 CST 2018, time=2018-01-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=276589, encodeId=3be72e65895f, content=学习了.涨知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Mon Jan 08 10:11:33 CST 2018, time=2018-01-08, status=1, ipAttribution=)]
    2018-01-09 thlabcde

    好资料学习了!

    0

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    2018-01-08 随梦飞扬

    0-II期胃炎患者上皮内瘤变风险为0.III期患者为每1000患者年36.5.IV期患者为每1000患者年63.1.

    0

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    2018-01-08 海之蓝

    学习

    0

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    2018-01-08 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

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