J Clin Periodontol: 富含白细胞和富含血小板的纤维蛋白块用于骨增强术

2018-05-21 MedSci MedSci原创

该研究的目的是用组织工程学方法研究新的骨引导再生术的效果。

该研究的目的是用组织工程学方法研究新的骨引导再生术的效果。

这项单一群组观察性研究评估了富含白细胞和富血小板的纤维蛋白(L-PRF)块用于上颌骨中水平方向骨增强的结果。 L-PRF块是通过将颗粒状生物材料与切碎的L-PRF膜以50:50的比例混合并加入液体纤维蛋白原将所有材料粘合起来。术后即刻和5-8个月后,通过连续锥束计算机断层扫描(Cbcts) 匹配对水平增强进行线性和体积评估。

结果发现,包括15个牙槽骨水平位点的10位患者(平均年龄50.7岁[±17.2])。术前和术后CBCT扫描的叠加显示,在离牙槽嵴顶2,6和10mm处测量的平均线性水平骨增量分别为4.6mm(±2.3),5.3mm(±1.2)和4.4mm(±2.3)。体积增加平均为1.05立方厘米(±0.7)。 5-8个月后吸收率平均为15.6%(±6.7)。

L-PRF块可能是一种适用于治疗牙槽嵴缺损的技术。

原始出处:

Simone Cortellini, et al. Leucocyte‐ and platelet‐rich fibrin block for bone augmentation procedure: A proof‐of‐concept study. Journal of Clinical Periodontology. 2018 May. doi:10.1111/jcpe.12877

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    2019-01-15 feather89
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    2018-06-01 zhangp831002

    好知识

    0

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    2018-05-21 惠映实验室

    学习了.谢谢分享.

    0

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    2018-05-21 wqkm

    ^_^^_^^_^

    0

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长骨开放骨折的骨感染率为4-64%,关节手术的骨感染率为近1%。治疗骨感染和感染相关的骨丧失非常重要。本研究通过一种新型油包水纳米悬浮液(S/O/N)方法组装银纳米颗粒(AgNPs)和羟基磷灰石纳米颗粒(HANPs)(SR-PM-Ag-HA)制备了雷奈酸锶(SR)负载的聚乳酸-乙醇酸共聚物(PLGA)微球,以实现骨诱导性和抗菌性能。 研究人员评估了微观结构、药物释放、生物相容性、骨诱导性和体