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Diabetes Care：1型糖尿病患者减肥手术后好处多多

2016-06-06 崔倩 译 MedSci原创

1型糖尿病减肥手术
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目前关于减肥手术对1型糖尿病（T1D）的影响数据很少。该研究的目的是量化减肥手术对肥胖1型糖尿病患者的总体影响。研究人员检索了PubMed，SCOPUS，知识ISI Web和谷歌学术从一开始到2015年12月的研究，以确定在成人肥胖1型糖尿病患者与减肥手术的所有相关研究。该研究共包括17项研究，107名参与者，包括10个案例系列和7个病例报告。总体而言，主要手术是胃旁路术（n=70;65％）。所有

目前关于减肥手术对1型糖尿病（T1D）的影响数据很少。该研究的目的是量化减肥手术对肥胖1型糖尿病患者的总体影响。

研究人员检索了PubMed、SCOPUS、知识ISI Web和谷歌学术从一开始到2015年12月的研究，以确定在成人肥胖1型糖尿病患者与减肥手术的所有相关研究。

该研究共包括17项研究，107名参与者，包括10个案例系列和7个病例报告。总体而言，主要手术是胃旁路术（n=70;65％）。所有的研究中都报告过体重显著减少。除了一个系列，其他系列都显示在体重调整每日胰岛素需要量显著减少。有可用数据的全部患者（n=96）术前和术后糖化血红蛋白（HbA1c）汇集平均值±SD分别为8.4±1.3％和7.9±1.1％（P=0.01）。除了常见的术后并发症，研究中还报道了血糖的严重变化（糖尿病酮症酸中毒和低血糖）和胃肠道动力障碍症状（长期性肠梗阻和急性胃扩张）。无手术死亡的报道。

肥胖T1D患者减肥手术后体重显著下降，并且胰岛素需求量和血糖状态显著改善。减肥手术的有利的代谢作用可以便于T1D患者的医疗管理，并减少心血管风险。糖尿病酮症酸中毒和低血糖是潜在的严重并发症。T1D患者减肥手术的短期结果是非常令人鼓舞的，但还需要较大的而且长期的研究。

原始出处：

John P. Kirwan，Ali Aminian，Sangeeta R. Kashyap，et al.Bariatric Surgery in Obese Patients With Type 1 Diabetes,Diabetes Care,2016.6.6

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    2016-09-23 木头人513

    #Diabetes#

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    2016-08-21 ms9608593228839890

    #DIA#

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    2017-04-09 millore

    #1型糖尿病患者#

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    2017-03-05 ms5439512287675881

    #BET#

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    2016-06-08 xue8604

    #糖尿病患者#

    0

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