JAHA：血清尿酸水平与老年人心血管疾病和全因死亡率之间的U形关系！

2018-02-11 xing.T MedSci原创

由此可见，SUA≥8或<4mg/dL可以独立预测老年人较高的全因和CVD相关死亡率，特别是营养不良者。

老年人血清尿酸（SUA）水平升高与心血管疾病（CVD）相关死亡率之间的联系仍然不明确。营养状况会影响SUA和CVD结局。近日，心血管疾病领域权威杂志JAHA上发表了一篇研究文章。研究人员调查了SUA能否预测老年人的死亡和营养不良对效应改变的作用。

研究人员将2001年至2010年期间参与台北市老年人健康体检项目中的127771名65岁以上成年人组成的台湾队列队列按照SUA每增加1mg/dL进行分层。根据老年营养风险指数<98，血清白蛋白<38g/L或体重指数<22kg/m2的营养不良状态分为低SUA（<4mg/dL）组。研究结局包括全因和CVD相关的死亡。在调整20个人口统计学指标和合并症变量后，研究人员使用Cox模型估计了死亡的风险比（HR）。

在中位随访5.8年后，共有16439例全因死亡和3877例CVD相关死亡参与者。相比于4mg/dL
由此可见，SUA≥8或<4mg/dL可以独立预测老年人较高的全因和CVD相关死亡率，特别是营养不良者。

原始出处：

Wei‐Cheng Tseng, et al. U‐Shaped Association Between Serum Uric Acid Levels With Cardiovascular and All‐Cause Mortality in the Elderly: The Role of Malnourishment.JAHA.2018. https://doi.org/10.1161/JAHA.117.007523

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2018-12-08 12498e67m28暂无昵称

#U形关系#

21 0
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2018-02-13 lvliquan

#全因死亡率#

22 0
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2018-02-13 zhaohui6731

#AHA#

21 0
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2018-02-13 feifers

#血清尿酸#

23 0
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2018-02-13 andy2090

#血管疾病#

20 0
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2018-02-11 1ddf0692m34(暂无匿称)

学习了.涨知识

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