CIRC RES:机器vs传统心血管危险评分

2017-08-21 MedSci MedSci原创

机器学习(Machine Learning, ML)是一门多领域交叉学科,可能有助于评估心血管危险因素,从而预测患者的预后。近日,在国际心血管权威杂志Circulation research上发表了一篇旨在评估机器学习-随机生存林(RF)与传统的心血管危险评分相比的特点的研究。本研究纳入了动脉粥样硬化的多种族研究(MESA)中的研究对象,随访12年,评估其心血管结局。最终,本研究纳入了6814名研

机器学习(Machine Learning, ML)是一门多领域交叉学科,可能有助于评估心血管危险因素,从而预测患者的预后。近日,在国际心血管权威杂志Circulation research上发表了一篇旨在评估机器学习-随机生存林(RF)与传统的心血管危险评分相比的特点的研究。

本研究纳入了动脉粥样硬化的多种族研究(MESA)中的研究对象,随访12年,评估其心血管结局。最终,本研究纳入了6814名研究对象,年龄范围是45至84岁,共进行了包括影像学、非侵入性检查、问卷调查和生物标志物检测等735个变量的检查,并通过随机生存林技术对每个结局预后的前20个心血管预测因素进行评估。其中,年龄是全因死亡的最重要预测因素,空腹血糖水平与颈动脉超声检查是卒中的重要预测因素,冠状动脉钙化积分是冠心病和动脉粥样硬化性疾病的最重要预测因素,左室结构和功能、心脏肌钙蛋白T是心衰的重要预测因素,肌酸酐、年龄和踝臂指数是房颤的重要预测因素,组织坏死因子α、白介素-2可溶性受体及N末端脑钠肽前体水平是所有心血管预后的重要预测因素。此外,随机生存林技术比传统的危险评分更精确(Brier评分下降10-25%)。

研究结果显示,机器学习技术在预测各种心血管结局预后方面比传统的危险评分更加准确。

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    2017-08-25 大爰

    学习并分享!!!

    0

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    2017-08-24 天涯183

    非常好的文章.学习了

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=236963, encodeId=5fae23696330, content=学习并分享!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Fri Aug 25 11:45:38 CST 2017, time=2017-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236707, encodeId=24a8236e07e1, content=非常好的文章.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Thu Aug 24 15:35:11 CST 2017, time=2017-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1583053, encodeId=9cab1583053fb, content=<a href='/topic/show?id=f6e1611840d' target=_blank style='color:#2F92EE;'>#机器#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61184, encryptionId=f6e1611840d, topicName=机器)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=13dc16973127, createdName=ms6279672939590805, createdTime=Wed Aug 23 01:33:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629763, encodeId=3c221629e63cd, content=<a href='/topic/show?id=28c351e80dc' target=_blank style='color:#2F92EE;'>#心血管危险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51780, encryptionId=28c351e80dc, topicName=心血管危险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e0221357465, createdName=lingaifan, createdTime=Wed Aug 23 01:33:00 CST 2017, time=2017-08-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=236081, encodeId=0d7b2360814a, content=非常好的文章.学习了.很受益, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Aug 22 17:51:23 CST 2017, time=2017-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235710, encodeId=2df5235e1052, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Mon Aug 21 15:27:11 CST 2017, time=2017-08-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=235690, encodeId=3d9f2356901a, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Mon Aug 21 12:52:20 CST 2017, time=2017-08-21, status=1, ipAttribution=)]
    2017-08-22 天涯183

    非常好的文章.学习了.很受益

    0

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    2017-08-21 楠博One

    学习谢谢分享

    0

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    2017-08-21 惠映实验室

    学习了,谢谢。

    0

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冠心病是女性健康的头号杀手,动脉的硬化程度可以预测心肌的梗塞,而绝经后女性的动脉顺应性(AC)较男性处于低水平。近日,在国际心血管权威杂志JAHA上发表了一篇旨在AC与冠脉栓塞和钙化在女性中的相关性的临床研究。本研究纳入了3639名无冠心病病史的成年人,冠脉的钙化程度通过Agatston法进行评估,AC指数通过心搏量指数/中心脉压来算得,并利用多元线性回归分析评估logAC指数与log(冠脉钙化评

JCEM:CT得到的体脂分布与心血管事件发生有何关系?

在一个多民族队列中,内脏脂肪,而不是皮下脂肪,与心血管疾病的风险显著相关。这些数据支持进行有效的生活方式改变策略来预防和减少内脏脂肪。

JAHA:成年代谢综合征与5岁以后的健康状况呈相关性!

关于代谢综合征(MetS)患者从青少年何时开始出现尚未形成统一定论。近日,在国际心血管权威杂志JAHA上发表了一篇旨在研究年龄与儿童代谢综合征与成人代谢综合征、2型糖尿病和颈动脉内中膜厚度的关系的临床研究。本研究纳入了来自4个队列的5803名参与者,平均随访时间是22.3年。研究结果显示,从5岁开始的儿童代谢综合征和超重患成人代谢综合征的风险要高2.4倍,而2型糖尿病的风险从8岁开始增加(RR,

Heart:中国学者揭示腰围增加可显著增加高血压发生风险

目前,高血压与腰围增加的相关性尚未阐明。本研究纳入了2007-2008年10265例中国农村进行体检的≥18岁的成年人,并将研究对象按照性别和腰围增加比例分为以下几组:≤?2.5%, ?2.5% - 2.5%, 2.5% - 5% 和 >5%。经过平均6年时间的随访,有2027名诊断为高血压,女性占1213名。从基线到随访结束,男性研究对象的腹型肥胖比例从21.1%增加至29.6%,女性从4

Lipids Health Dis:北大武阳丰教授等研究称,我国急性冠脉事件患者半年后仅七成用他汀,停药者心血管事件易复发

北京大学临床研究所、乔治全球健康研究院武阳丰教授等报告,我国出院时处方了他汀类药物(他汀)的急性冠脉综合征(ACS)患者,出院6个月时他汀应用率降至了72%。