Radiology:声脉冲辐射弹性成像在肢体淋巴性水肿组织纤维化评价

2019-03-15 shaosai MedSci原创

本研究旨在利用声辐射脉冲(ARFI)弹性成像在评价肢体淋巴性水肿患者皮肤及皮下组织弹性指标的可能性。

本研究旨在利用声辐射脉冲(ARFI)弹性成像在评价肢体淋巴性水肿患者皮肤及皮下组织弹性指标的可能性。

本研究共纳入了64例行US筛查出淋巴性水肿的患者。利用剪切波速(SWV)定量测量皮肤及皮下肢体组织弹性度。以淋巴显像为参考标准。

结果为,淋巴回流受阻肢体的SWV要明显高于正常肢体(皮肤组织:2.75 m/sec vs 1.74 m/sec,皮下组织:1.90 m/sec vs 1.35 m/sec; P < .001)。在无淋巴回流受阻、部分淋巴回流受阻和完全临床受阻肢体中SWV具有显着差异性。(皮肤组织: 1.74 m/sec vs 2.75 m/sec vs 2.77 m/sec; 皮下组织: 1.35 m/sec vs 1.90 m/sec vs 1.90 m/sec; P < .001)。以2.10 m/sec、1.43 m/sec分别为皮肤组织和皮下组织的最佳截断值,淋巴回流受阻的敏感性分别为83.1% (59 / 71) 、 80.3% (57 / 71),特异性分别为86.0% (49 / 57) 、 70.2% (40 / 57)。ROC相关曲线下面积分别为0.91 、 0.83。

本研究表明,声辐射脉冲弹性成像显示淋巴性水肿肢体的皮肤及皮下组织要比正常肢体僵硬。声辐射脉冲弹性成像有可能作为纤维化定量评价的非侵入性影像学方法。

原始出处:

Chan WH, Huang YL, Lin C,et al.Acoustic Radiation Force Impulse Elastography: Tissue Stiffness Measurement in Limb Lymphedema.Radiology.DOI:10.1148/radiol.2018172869

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    2019-03-17 小华子
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    2019-03-17 jiyangfei
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    2019-03-17 huagfeg
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    2019-03-15 orangesking

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