Head Neck Pathol:鼻中隔弯曲对鼻上皮的影响

2017-05-23 AlexYang MedSci原创

鼻阻塞是当今ENT外科医生每天医疗实践中最常见的疾病之一。鼻中隔弯曲是鼻阻塞最为常见的原因。鼻中隔弯曲可以改变气道动态流动,这可以导致鼻粘膜各种各样的组织病理学变化。最近,有研究人员对组织病理学变化,比如淋巴细胞性浸润和鳞状上皮化生,在凹凸面进行了研究和比较。该预期随机性研究包括了42名鼻中隔弯曲的病人,这些病人是从 KLES Dr. Prabhakar Kore医院和医疗中心的耳鼻喉科住院部,并

鼻阻塞是当今ENT外科医生每天医疗实践中最常见的疾病之一。鼻中隔弯曲是鼻阻塞最为常见的原因。鼻中隔弯曲可以改变气道动态流动,这可以导致鼻粘膜各种各样的组织病理学变化。最近,有研究人员对组织病理学变化,比如淋巴细胞性浸润和鳞状上皮化生,在凹凸面进行了研究和比较。该预期随机性研究包括了42名鼻中隔弯曲的病人,这些病人是从 KLES Dr. Prabhakar Kore医院和医疗中心的耳鼻喉科住院部,并在2015年1月到12月召集的。

研究结果发现,隔黏膜淋巴细胞性浸润和鳞状上皮化生在凹面比凸面比例更高。更多的是,在凹面的横向壁黏膜中,淋巴细胞性浸润和鳞状上皮化生与图面比较有所增加,但是,差异并不显著。鼻中隔弯曲导致鼻粘膜更倾向于慢性炎症和鳞状上皮化生,原因是气道的改变。由于病理生理学的变化,病人对慢性鼻炎和鼻窦炎更加敏感。

原始出处:

Kumar L, Belaldavar BP, Bannur H et al. Influence of Deviated Nasal Septum on Nasal Epithelium: An Analysis. Head Neck Pathol. 4 May 2017.

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    2018-03-10 yb6560
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