糖尿病重磅消息！全球每周一次口服降糖药Zafatek获批！

2015-03-26 佚名生物谷

日本制药巨头武田（Takeda）近日宣布，糖尿病新药Zafatek（trelagliptin succinate，曲格列汀琥珀酸盐）获日本卫生劳动福利部（MHLW）批准，用于2型糖尿病的治疗。此次批准，标志着Zafatek成为全球上市的首个每周口服一次的降糖药，同时也代表着武田在糖尿病市场投下的一枚重磅炸弹！ Zafatek由武田和Furiex研发，该药是一种超长效二肽基肽酶IV（DPP-4）抑

日本制药巨头武田（Takeda）近日宣布，糖尿病新药Zafatek（trelagliptin succinate，曲格列汀琥珀酸盐）获日本卫生劳动福利部（MHLW）批准，用于2型糖尿病的治疗。此次批准，标志着Zafatek成为全球上市的首个每周口服一次的降糖药，同时也代表着武田在糖尿病市场投下的一枚重磅炸弹！

Zafatek由武田和Furiex研发，该药是一种超长效二肽基肽酶IV（DPP-4）抑制剂，每周口服一次，而市场上同类DPP-4抑制剂需要每天口服一次，Zafatek的用药优势无疑将为糖尿病患者提供了更为方便的治疗选择，有望大幅改善患者的便利性和依从性。

目前，美国制药巨头默沙东（Merck）也正在开发一款超长效DPP-4抑制剂omarigliptin，该公司于去年底向日本提交了全球首个监管申请。在临床试验中，omarigliptin疗效媲美自身年销40亿美元的每日一次DPP-4抑制剂Januvia（捷诺维，sitagliptin，西他列汀）。业界认为，omarigliptin将成为默沙东捍卫其口服降糖药市场霸主地位的重要筹码。

据了解，DPP-4抑制剂是首类可通过提高机体自身能力控制血糖水平的新型2型糖尿病药物，可用作单药，也可与其它口服降糖药联用，其作用机制独特，具有不产生低血糖、不引起体重增加，以及副作用小等独特优势，同时引起胃肠道不良反应的发生率亦很低。

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2015-08-30 12498bd5m16暂无昵称

#fat#

26 0
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2015-06-11 ljjj1053

好好学习一下

155 0
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2015-05-24 zhaohongyun

期待omarigliptin上市

91 0
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2015-04-23 CCLJ

如果是真的有效那就太好了，赶紧流入中国吧

120 0
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2015-04-11 x35042875

AKI对心衰临床治疗意义重大，但依然需要研究检验其适用性

59 0
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2015-03-30 MedSci客户端网友

贵族药。

104 0
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2015-03-30 fantasticer

一周一次是不是很容易忘记？

130 0
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2015-03-28 minlingfeng

#降糖药#

27 0
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2015-03-28 hunizi005

#口服降糖药#

31 0
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2015-03-28 xxxx1054

#重磅#

20 0

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