Radiology:雌激素受体阳性乳腺癌复发风险?定性放射基因学组来说道说道!

2017-10-04 shaosai MedSci原创

乳腺癌Breast Cancer是目前全球女性中发病最高的恶性肿瘤,是一种全身性疾病,乳腺位置及乳腺癌示意图在早期即可发生腋淋巴结转移,因此在治疗策略上早期发现并阻断其转移对乳腺癌的治疗及预后具有重大的临床意义。而浸润性乳腺癌是乳腺癌的主要类型严重危害着女性的身心健康。本研究旨在评价雌激素受体阳性乳腺癌患者乳腺影像学报告和数据系统(BI-RADS)乳腺X线摄影和磁共振(MR)成像特征与乳腺复发风险

乳腺癌Breast Cancer是目前全球女性中发病最高的恶性肿瘤,是一种全身性疾病,乳腺位置及乳腺癌示意图在早期即可发生腋淋巴结转移,因此在治疗策略上早期发现并阻断其转移对乳腺癌的治疗及预后具有重大的临床意义。而浸润性乳腺癌是乳腺癌的主要类型严重危害着女性的身心健康。本研究旨在评价雌激素受体阳性乳腺癌患者乳腺影像学报告和数据系统(BI-RADS)乳腺X线摄影和磁共振(MR)成像特征与乳腺复发风险的相关性,并将结果发表在Radiology上。

本研究共纳入了自2003年至2013年间408例被诊断为侵袭性乳腺癌的患者,并行肿瘤类型诊断鉴定。根据BI-RADS词录,回顾性分析乳腺X摄影和MRI特征。利用线性回归分析影像学特征和肿瘤类型DX检测复发评分(ODxRS),利用事后两两比较评价ODxRS。

结果为,乳腺X线摄影乳腺密度与ODxRS (P ≤ .05)呈负相关。密度分类A和D平均ODxRS 分别为24.4、16.5 (P < .02)。乳腺X线摄影图像中边界模糊或清晰条状钙化均与高ODxRS具有显着相关性(分别为P < .01、P < .03)。边界模糊的肿块ODxRS平均为31.3,与其他所有肿块边界ODxRS(18.5)明显不同(P < .01)。清晰条状钙化的平均ODxRS为29.6,而其他可疑为钙化的形态结构为19.4(P<.03)。在MR图像中,与有毛刺肿块相比,不规则边界肿块的平均ODxRS要高(24.0 vs 17.6; P < .02)。MR检查中无强化肿块与低ODxRS具有相关性。

本研究表明,乳腺密度、钙化形态、乳腺X线摄影和MR成像中肿块边界和MR成像中无强化肿块特点可作为乳腺癌复发风险的潜在性影像学标识物。

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    2017-10-08 ren1mw

    乳腺密度.钙化形态.乳腺X线摄影和MR成像中肿块边界和MR成像中无强化肿块特点可作为乳腺癌复发风险的潜在性影像学标识物

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1980841, encodeId=6cf31980841e1, content=<a href='/topic/show?id=aaf6668192d' target=_blank style='color:#2F92EE;'>#激素受体阳性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66819, encryptionId=aaf6668192d, topicName=激素受体阳性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Mon Oct 09 06:42:00 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1905478, encodeId=3cc419054e85d, content=<a href='/topic/show?id=0eb34259ea1' target=_blank style='color:#2F92EE;'>#复发风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42597, encryptionId=0eb34259ea1, topicName=复发风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sat May 19 08:42:00 CST 2018, time=2018-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251270, encodeId=94832512e00e, content=乳腺密度.钙化形态.乳腺X线摄影和MR成像中肿块边界和MR成像中无强化肿块特点可作为乳腺癌复发风险的潜在性影像学标识物, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Oct 08 07:30:58 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503480, encodeId=aac91503480d9, content=<a href='/topic/show?id=59d798e61f0' target=_blank style='color:#2F92EE;'>#雌激素受体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98761, encryptionId=59d798e61f0, topicName=雌激素受体)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae6c9649886, createdName=surilei, createdTime=Fri Oct 06 13:42:00 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250448, encodeId=4be125044878, content=学习了.好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Oct 05 07:19:44 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250433, encodeId=07b82504330c, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Thu Oct 05 07:00:08 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250393, encodeId=1305250393bf, content=不错的文章值得一读., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Oct 04 23:13:30 CST 2017, time=2017-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250392, encodeId=fa7d2503923a, content=学习了不少事情!, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4BGdu4COj6QWFqgMd3xnWDdgLZKUGI32veZvO2qFAQvpYr1eMbUOTqMvlZWc3MsugtFMHzxDwial/0, createdBy=88731939304, createdName=圣艮山, createdTime=Wed Oct 04 23:13:27 CST 2017, time=2017-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250390, encodeId=789325039082, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KiblTyxD95ExbzUoCVcRuhPibXboL28wicFMTXUhCA0RWCyQZYC5Na3ap7CxjialMkB50VEJ0XToQQTC/0, createdBy=470c1945776, createdName=方舒, createdTime=Wed Oct 04 22:46:58 CST 2017, time=2017-10-04, status=1, ipAttribution=)]
    2017-10-05 1ddf0692m34(暂无匿称)

    学习了.好文章

    0

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    2017-10-05 明月清辉

    谢谢分享.学习了

    0

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    2017-10-04 1e1b8538m79(暂无匿称)

    不错的文章值得一读.

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1980841, encodeId=6cf31980841e1, content=<a href='/topic/show?id=aaf6668192d' target=_blank style='color:#2F92EE;'>#激素受体阳性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66819, encryptionId=aaf6668192d, topicName=激素受体阳性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5662228, createdName=mjldent, createdTime=Mon Oct 09 06:42:00 CST 2017, time=2017-10-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1905478, encodeId=3cc419054e85d, content=<a href='/topic/show?id=0eb34259ea1' target=_blank style='color:#2F92EE;'>#复发风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42597, encryptionId=0eb34259ea1, topicName=复发风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ca20190, createdName=wushaoling, createdTime=Sat May 19 08:42:00 CST 2018, time=2018-05-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=251270, encodeId=94832512e00e, content=乳腺密度.钙化形态.乳腺X线摄影和MR成像中肿块边界和MR成像中无强化肿块特点可作为乳腺癌复发风险的潜在性影像学标识物, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sun Oct 08 07:30:58 CST 2017, time=2017-10-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1503480, encodeId=aac91503480d9, content=<a href='/topic/show?id=59d798e61f0' target=_blank style='color:#2F92EE;'>#雌激素受体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98761, encryptionId=59d798e61f0, topicName=雌激素受体)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae6c9649886, createdName=surilei, createdTime=Fri Oct 06 13:42:00 CST 2017, time=2017-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250448, encodeId=4be125044878, content=学习了.好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220115/46bcf39c32de4aa6b45c5f9d66c8ee77/6cb4a20c55bb4b7691122f47747bfca2.jpg, createdBy=9dad1662329, createdName=1ddf0692m34(暂无匿称), createdTime=Thu Oct 05 07:19:44 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250433, encodeId=07b82504330c, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Thu Oct 05 07:00:08 CST 2017, time=2017-10-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250393, encodeId=1305250393bf, content=不错的文章值得一读., beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=eff51996281, createdName=1e1b8538m79(暂无匿称), createdTime=Wed Oct 04 23:13:30 CST 2017, time=2017-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250392, encodeId=fa7d2503923a, content=学习了不少事情!, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4BGdu4COj6QWFqgMd3xnWDdgLZKUGI32veZvO2qFAQvpYr1eMbUOTqMvlZWc3MsugtFMHzxDwial/0, createdBy=88731939304, createdName=圣艮山, createdTime=Wed Oct 04 23:13:27 CST 2017, time=2017-10-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=250390, encodeId=789325039082, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KiblTyxD95ExbzUoCVcRuhPibXboL28wicFMTXUhCA0RWCyQZYC5Na3ap7CxjialMkB50VEJ0XToQQTC/0, createdBy=470c1945776, createdName=方舒, createdTime=Wed Oct 04 22:46:58 CST 2017, time=2017-10-04, status=1, ipAttribution=)]
    2017-10-04 圣艮山

    学习了不少事情!

    0

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    2017-10-04 方舒

    学习

    0

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