Ophthalmologica:光学相干断层扫描血管造影检查数据发现深层血管层改变对糖尿病视网膜病变发病机制具有重要意义

2019-02-16 不详 网络

日本宇治市Sensho-kai眼科研究所的Dimitrova G和Chihara E等人近日在Ophthalmologica发表了一项重要的工作,他们进行了文献综述研究,通过分析来自糖尿病患者的浅表和深层血管层检测报告的光学相干断层扫描血管造影(OCTA)参数,并评估这些参数与糖尿病视网膜病变(DR)发病机制的相关性。

日本宇治市Sensho-kai眼科研究所的Dimitrova G和Chihara E等人近日在Ophthalmologica发表了一项重要的工作,他们进行了文献综述研究,通过分析来自糖尿病患者的浅表和深层血管层检测报告的光学相干断层扫描血管造影(OCTA)参数,并评估这些参数与糖尿病视网膜病变(DR)发病机制的相关性。

他们通过Medline / PubMed进行文献检索,检索了2015年1月至2018年8月间发表的关于OCTA在糖尿病中应用的论文。这些OCTA研究表明,所有糖尿病患者的视网膜血管层的参数都有所改变。从所有纳入研究的关于浅表和深部血管层的案例中研究发现,许多研究表明深部血管层在DR发展的早期阶段受到影响。DR患者深部血管层OCTA参数改变比浅表血管层更明显,糖尿病性黄斑水肿患者深部血管层改变最明显。

因此,作者认为,视网膜静脉起源于视网膜的深血管层,糖尿病患者深血管层中OCTA参数的改变可能意味着视网膜血管系统的静脉侧在DR的发病机理中的主要影响。

原文出处:

Dimitrova, G. and E. Chihara, Implication of Deep-Vascular-Layer Alteration Detected by Optical Coherence Tomography Angiography for the Pathogenesis of Diabetic Retinopathy. Ophthalmologica, 2019: p. 1-4.

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    2019-02-18 zutt
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    2019-02-18 sodoo
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    2019-02-18 zhouqu_8
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    2019-02-16 misszhang

    谢谢MedSci提供最新的资讯

    0