BMJ:不同饮食模式与痛风的风险有啥关系?

2017-05-11 xing.T MedSci原创

DASH饮食与痛风风险较低有关,提示高尿酸血症患者降低尿酸水平可降低痛风发生风险。相反,西方饮食与更高的痛风风险相关。DASH饮食可能为男性痛风的风险提供一个有吸引力的预防性饮食策略。

近日,顶级杂志BMJ上发表一篇研究文章,研究人员前瞻性地评估了男性膳食方法阻止高血压(DASH)饮食和西方饮食与痛风(即高尿酸血症的临床终点)风险之间相关性。

该研究采用前瞻性队列研究,在健康专业人员中进行随访研究。 44444名无基础痛风病史的参与者,研究人员采用经过验证的食物频率问卷,每个参与者都被分配一个DASH饮食模式得分(基于高摄入水果、蔬菜、坚果和豆类、低脂乳制品、全谷物类,低钠、低糖饮料,低红色和加工肉类摄入)和西方膳食模式得分(基于高红肉和加工肉、炸薯条、精制谷物、糖果和甜点摄入量)。发生痛风的风险符合美国风湿病学会痛风初级标准,调整潜在的混杂因素,包括年龄、体重指数、高血压、利尿剂使用和酒精摄入。

在26年的随访中,共有1731例痛风确诊病例发生。研究人员发现较高的DASH饮食模式得分与较低的痛风发生风险相关(极端五分之一参与者调整后的相对风险为0.68,95%可信区间为0.57-0.80,趋势P<0.001)。与此相反,较高的西方饮食模式得分与痛风发生风险增加相关(1.42,1.16-1.74,P=0.005)。

DASH饮食与痛风风险较低有关,提示高尿酸血症患者降低尿酸水平可降低痛风发生风险。相反,西方饮食与更高的痛风风险相关。DASH饮食可能为男性痛风的风险提供一个有吸引力的预防性饮食策略。

原始出处:

Sharan K Rai, et al.The Dietary Approaches to Stop Hypertension (DASH) diet, Western diet, and risk of gout in men: prospective cohort study.BMJ.2017.http://www.bmj.com/content/357/bmj.j1794

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    2018-02-26 gaoxiaoe
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    2017-05-17 QFXL123456

    学习了,谢谢

    0

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content=关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Thu May 11 09:59:08 CST 2017, time=2017-05-11, status=1, ipAttribution=)]
    2017-05-16 lou.minghong

    学习

    0

  4. 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content=关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Thu May 11 09:59:08 CST 2017, time=2017-05-11, status=1, ipAttribution=)]
    2017-05-13 liuyaoliliuyaoli

    拜读

    0

  5. 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content=关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Thu May 11 09:59:08 CST 2017, time=2017-05-11, status=1, ipAttribution=)]
    2017-05-13 jyzxjiangqin

    饮食与痛风的风险相关。

    0

  6. 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content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Fri May 12 09:59:49 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196592, encodeId=8179196592f1, content=痛风的问题如此严重。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Thu May 11 11:07:22 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196578, encodeId=8ff41965e83e, content=关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Thu May 11 09:59:08 CST 2017, time=2017-05-11, status=1, ipAttribution=)]
    2017-05-12 1e10c84am36(暂无匿称)

    文章不错,拜读了

    0

  8. 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channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101242, encryptionId=388a10124247, topicName=饮食模式)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=28de10689201, createdName=ms6519009802973839, createdTime=Fri May 12 23:04:00 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197019, encodeId=75c419e019f2, content=文章不错,拜读了, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri May 12 10:03:49 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=197015, encodeId=4db019e01511, content=学习了谢谢了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Fri May 12 09:59:49 CST 2017, time=2017-05-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196592, encodeId=8179196592f1, content=痛风的问题如此严重。, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Thu May 11 11:07:22 CST 2017, time=2017-05-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=196578, encodeId=8ff41965e83e, content=关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Thu May 11 09:59:08 CST 2017, time=2017-05-11, status=1, ipAttribution=)]
    2017-05-12 186****0580(小山羊)

    学习了谢谢了。

    0

  9. 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content=关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Thu May 11 09:59:08 CST 2017, time=2017-05-11, status=1, ipAttribution=)]
    2017-05-11 130****4638

    痛风的问题如此严重。

    0

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content=关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=01bb1684217, createdName=医张生, createdTime=Thu May 11 09:59:08 CST 2017, time=2017-05-11, status=1, ipAttribution=)]
    2017-05-11 医张生

    关键是怎么样无副作用的排走尿酸或者减少尿酸的产生。

    0