JAMA Intern Med:十国数据揭示软饮与死亡率之间的关系

2019-09-06 海北 MedSci原创

软饮料消费是一种常见的习惯,但这种消费是否与死亡风险相关尚不得知。

软饮料消费是一种常见的习惯,但这种消费是否与死亡风险相关尚不得知。而且,迄今为止,在欧洲人群中该关联尚未得到充分研究。

最近,研究人员探究了总糖,含糖和人工增甜的软饮料消费与随后的总体和原因特异性死亡率之间的关系。

这项基于人群的队列研究涉及欧洲癌症和营养前瞻性调查(EPIC)的参与者(全队列中的451743名),这是一个来自10个欧洲国家的持续的大型跨国人群(丹麦,法国,德国,希腊,意大利,荷兰,挪威,西班牙,瑞典和英国)。参加者于199211日至20001231日期间招募。被排除的参与者是基线时报告癌症,心脏病,中风或糖尿病的人群;或者有难以置信的膳食摄入数据的人群;和那些缺少软饮料或后续信息的人。

数据分析从201821日到2018101日进行。主要结果为总死亡率和原因特定死亡率。

研究人员使用针对其他死亡风险因素调整的多变量Cox比例风险回归模型估算危险比(HRs)和95CI

该研究总共招募了521330人。其中451743例(86.7%)纳入研究,平均(SD)年龄为50.89.8)岁,女性为32108171.1%)名。

16.4年(希腊为11.1至法国为19.2)的平均(范围)随访期间,发生了41693例死亡。每天食用2杯或更多杯(相对于每月<1杯)总软饮料的风险比[HR]1.17; 95CI1.11-1.22; P < .001),含糖软饮料(HR1.08; 95CI1.01-1.16; P = .004);人工加糖软饮料(HR1.26; 95CI1.16-1.35; P <.001 )。

研究人员在人工加糖的软饮料和循环系统疾病死亡之间也观察到正相关(每天≥2vs每月<1; HR1.52; 95CI1.30-1.78; P <.001),在加糖软饮料和消化系统疾病死亡之间也存在正相关(每天≥1vs每月<1; HR1.59; 95CI1.24-2.05; P <.001)。

因此,这项研究发现,在这个大型欧洲队列中,全部,含糖和人工加糖的软饮料的消费与全因死亡呈正相关;结果支持旨在限制软饮料消费的公共卫生运动。


原始出处:

Amy Mullee et al. Association Between Soft Drink Consumption and Mortality in 10 European Countries. JAMA Internal Medicine, 2019; DOI: 10.1001/jamainternmed.2019.2478


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    2019-11-02 146f671bm06暂无昵称

    尽量减少软饮

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    2019-09-18 qingfengqishi5

    学习了,学习了

    0

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    2019-09-15 qingfengqishi5

    学习了,学习了

    0

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    2019-09-12 qingfengqishi5

    学习了,学习了

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=374714, encodeId=155b3e471442, content=尽量减少软饮, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1a5a5180477, createdName=146f671bm06暂无昵称, createdTime=Sat Nov 02 17:21:21 CST 2019, time=2019-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372892, encodeId=34a03e289276, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Wed Sep 18 20:00:55 CST 2019, time=2019-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372768, encodeId=88bb3e2768f3, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Sun Sep 15 20:59:20 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372643, encodeId=36853e264313, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Thu Sep 12 23:14:09 CST 2019, time=2019-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372465, encodeId=de533e2465d2, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Sun Sep 08 21:26:47 CST 2019, time=2019-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609976, encodeId=733b16099e698, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Sep 08 11:27:00 CST 2019, time=2019-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372369, encodeId=e47b3e236979, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Fri Sep 06 21:31:52 CST 2019, time=2019-09-06, status=1, ipAttribution=)]
    2019-09-08 qingfengqishi5

    学习了,学习了

    0

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  7. [GetPortalCommentsPageByObjectIdResponse(id=374714, encodeId=155b3e471442, content=尽量减少软饮, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1a5a5180477, createdName=146f671bm06暂无昵称, createdTime=Sat Nov 02 17:21:21 CST 2019, time=2019-11-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372892, encodeId=34a03e289276, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Wed Sep 18 20:00:55 CST 2019, time=2019-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372768, encodeId=88bb3e2768f3, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Sun Sep 15 20:59:20 CST 2019, time=2019-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372643, encodeId=36853e264313, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=76, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Thu Sep 12 23:14:09 CST 2019, time=2019-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372465, encodeId=de533e2465d2, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Sun Sep 08 21:26:47 CST 2019, time=2019-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609976, encodeId=733b16099e698, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Sun Sep 08 11:27:00 CST 2019, time=2019-09-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372369, encodeId=e47b3e236979, content=学习了,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzTetibytbqFDmFITWHyBWbxU7S9MYibgPSqvu0sYteH0N6zXqbU0Kf3Mbdb7yWM1Kud3zPgYBibE2SZ/0, createdBy=da7696924, createdName=qingfengqishi5, createdTime=Fri Sep 06 21:31:52 CST 2019, time=2019-09-06, status=1, ipAttribution=)]
    2019-09-06 qingfengqishi5

    学习了,学习了

    0