Radiology:计算机辅助诊断到底行不行?

2017-12-25 shaosai MedSci原创

本研究旨在通过利用对比增强US电影剪辑资料评估计算机辅助诊断(CAD)系统的价值并确定鉴别良恶性肝局灶性病变(FLLs)的主要US征象。研究人员将结果发表在Radiology上。

本研究旨在通过利用对比增强US电影剪辑资料评估计算机辅助诊断(CAD)系统的价值并确定鉴别良恶性肝局灶性病变(FLLs)的主要US征象。研究人员将结果发表在Radiology上。

本研究共纳入了106例FLL患者的超声资料,其中包括良性51例、恶性54例及1例间变性。共有105例FLL经过组织学检查、对比增强CT、动态增强MRI和(或)>6个月的临床随访。数据包括3分钟的电影剪辑并经过自动校正。B型和对比特异性征象被提取,在模拟神经网络(ANN)和支持向量机(SVM)上进行分析。比较CAD与一个高年资和低年资阅片者的ROC曲线下面积(AUC)。另外一个阅片者对电影剪辑质量进行分级从而评价其对CAD能力的影响。

结果为,CAD、低年资阅片者和高年资阅片者能够分析的电影剪辑数量分别为95、100、102。SVM、ANN、高年资阅片者和低年资阅片者的AUC分别为0.883 (95% confidence interval [CI]: 0.793, 0.940)、0.829 (95% CI: 0.724, 0.901)、0.843 (95% CI: 0.756, 0.903)和0.702 (95% CI: 0.586, 0.782),仅在SVM和低年资阅片者间具有统计学差异。当CAD结果与低年资阅片者一致时,准确率从71.3% (67 of 94; 95% CI: 60.6%, 79.8%)提高到87.7% (57 of 65; 95% CI: 78.5%, 93.8%) ,而当CAD结果与高年资阅片者一致时,准确率从80.9% (76 of 94; 95% CI: 72.3%, 88.3%)提高到 90.3% (65 of 72; 95% CI: 80.6%, 95.8%)。CAD在所有的迭代过程中B型回声不均质和对比剂的廓清是最具有鉴别能力的征象。CAD选择的基于时间的时间强度曲线(TIC)(99.0% (207 of 209))的价值要明显高于基于强度的TIC(1.0% (two of 209))。15个影像质量标准对CAD的准确性的影响均无统计学差异。

本研究表明,CAD系统能够鉴别FLL的良恶性,其准确率不亚于专业阅片者。同时,CAD能够提高阅片者的准确率。基于时间的TIC特征在鉴别时要优于基于强度的特征。

原始出处:

Ta CN, Kono Y, Eghtedari M. et al.Focal Liver Lesions: Computer-aided Diagnosis by Using Contrast-enhanced US Cine Recordings.Radiology.DOI: 10.1148/radiol.2017170365

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1716384, encodeId=194c1e163844e, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Thu Jun 14 22:39:00 CST 2018, time=2018-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273507, encodeId=73422e35073c, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Dec 29 13:04:51 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272450, encodeId=e1fd2e24507f, content=客观性.公正性.讲得很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Mon Dec 25 18:23:13 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272433, encodeId=42302e2433e5, content=好好学习天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Dec 25 15:26:01 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272414, encodeId=065f2e241453, content=谢谢分享. , beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Mon Dec 25 11:55:40 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272381, encodeId=1d562e2381ee, content=未来体检筛查的利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/25/4b9d1be58c365b6b776f1c5a557fd1f4.jpg, createdBy=0b042231191, createdName=Yqasim, createdTime=Mon Dec 25 10:43:27 CST 2017, time=2017-12-25, status=1, ipAttribution=)]
    2018-06-14 bioon14
  2. [GetPortalCommentsPageByObjectIdResponse(id=1716384, encodeId=194c1e163844e, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Thu Jun 14 22:39:00 CST 2018, time=2018-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273507, encodeId=73422e35073c, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Dec 29 13:04:51 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272450, encodeId=e1fd2e24507f, content=客观性.公正性.讲得很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Mon Dec 25 18:23:13 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272433, encodeId=42302e2433e5, content=好好学习天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Dec 25 15:26:01 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272414, encodeId=065f2e241453, content=谢谢分享. , beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Mon Dec 25 11:55:40 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272381, encodeId=1d562e2381ee, content=未来体检筛查的利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/25/4b9d1be58c365b6b776f1c5a557fd1f4.jpg, createdBy=0b042231191, createdName=Yqasim, createdTime=Mon Dec 25 10:43:27 CST 2017, time=2017-12-25, status=1, ipAttribution=)]
    2017-12-29 虈亣靌

    学习一下谢谢分享

    0

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    2017-12-25 虈亣靌

    客观性.公正性.讲得很不错

    0

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    2017-12-25 shaosai

    好好学习天天向上

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1716384, encodeId=194c1e163844e, content=<a href='/topic/show?id=d68d911542f' target=_blank style='color:#2F92EE;'>#计算机#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91154, encryptionId=d68d911542f, topicName=计算机)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=def632217870, createdName=bioon14, createdTime=Thu Jun 14 22:39:00 CST 2018, time=2018-06-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=273507, encodeId=73422e35073c, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Fri Dec 29 13:04:51 CST 2017, time=2017-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272450, encodeId=e1fd2e24507f, content=客观性.公正性.讲得很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Mon Dec 25 18:23:13 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272433, encodeId=42302e2433e5, content=好好学习天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLANEL7Sww3HicKsN9aribicAmGGWXOIMEiaZ1iadgZg9RibjqSwIKUS8gSPib2NwTVg2zVvVJhdP3BkuDIl/0, createdBy=944d1605392, createdName=shaosai, createdTime=Mon Dec 25 15:26:01 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272414, encodeId=065f2e241453, content=谢谢分享. , beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Mon Dec 25 11:55:40 CST 2017, time=2017-12-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=272381, encodeId=1d562e2381ee, content=未来体检筛查的利器, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/12/25/4b9d1be58c365b6b776f1c5a557fd1f4.jpg, createdBy=0b042231191, createdName=Yqasim, createdTime=Mon Dec 25 10:43:27 CST 2017, time=2017-12-25, status=1, ipAttribution=)]
    2017-12-25 doctorJiangchao

    谢谢分享.

    0

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    2017-12-25 Yqasim

    未来体检筛查的利器

    0