J Affect Disord:产后抑郁?男士们注意啦!快看自家老婆是否有这个症状?

2018-09-25 牛艳红 医师报

近日,一项芬兰研究表明,有妊娠期糖尿病的孕妇出现产后抑郁症状的风险升高。(J Affect Disord. 2018,241:263)


近日,一项芬兰研究表明,有妊娠期糖尿病的孕妇出现产后抑郁症状的风险升高。(J Affect Disord. 2018,241:263)

研究纳入1066例没有心理健康问题的孕妇,并采用爱丁堡产后抑郁量表评估其妊娠晚期和产后8周时的抑郁症状,有505例在妊娠初期也接受了抑郁症状评估。

结果发现,在总研究人群中,妊娠期糖尿病和产后抑郁症状的患病率分别为14.1%和10.3%。在诊断和未诊断妊娠期糖尿病的女性中,分别有16%和9%出现产后抑郁症状。校正混杂因素后,妊娠期糖尿病与产后抑郁症状发生风险增加1.23倍相关。而且,在对有妊娠初期抑郁数据女性的亚组分析也同样发现,妊娠期糖尿病与产后抑郁症状显著相关。

研究者从两个方面解释了这一观察结果。首先,从心理机制来看,在怀孕期间被诊断出可能会伤害胎儿的疾病可能是一种压力体验,这可能会导致孕产妇的抑郁症状。其次,在生理机制上,糖代谢受损可能会增强细胞因子介导的低度炎症,而低度炎症与抑郁有关。先前也有相关研究表明,2型糖尿病患者易患抑郁症,而抑郁症患者也易患2型糖尿病。

未来应进一步研究对妊娠期糖尿病女性在怀孕期间和产后进行更密切的随访或支持性干预,能否使其免于发生产后抑郁症状。

原始出处:

Aleksi Ruohom?ki,et al.The association between gestational diabetes mellitus and postpartum depressive symptomatology: A prospective cohort study.J Affect Disord.DOI: https://doi.org/10.1016/j.jad.2018.08.070

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    2019-06-15 chenwq08
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