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JAMA：中年饮食模式与痴呆风险

2019-03-13 zhangfan MedSci原创

痴呆饮食模式中年人群
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研究认为，中年人群饮食模式与痴呆风险无显著相关性

观察研究发现饮食模式与认知健康有关。近日研究人员开展队列研究考察了中年饮食模式与痴呆风险的相关性

研究于1985-1988年开始，分别在1991-93、1997-99、2002-04年间对参与者日常饮食情况进行考察，随访至2017年3月，通过食物摄入问卷的形式评估健康饮食指数(AHEI，0-110，分数越高饮食越健康)，研究的主要终点为痴呆症。

1991-93年间，8225名基线无痴呆症状的中年人参与研究，平均年龄50.2岁，男性占69.1%。在24.8年的随访期间总计发生了344例痴呆病例。1991-93、1997-99、2002-04期间未发现AHEI差异与痴呆的相关性。1991-1993年间，AHEI得分最低1/3人群每1000随访年的痴呆发病1.76例，与中间人群以及最高1/3人群的风险差异仅为0.03和0.04。1997-1999年间，AHEI得分最低1/3人群每1000随访年的痴呆发病2.06例，与中间人群以及最高1/3人群的风险差异仅为0.14和0.14。2002-2004年间，AHEI得分最低1/3人群每1000随访年的痴呆发病3.12例，与中间人群以及最高1/3人群的风险差异仅为0.61和0.73。

研究认为，中年人群饮食模式与痴呆风险无显著相关性。

原始出处：

Tasnime N. Akbaraly et al. Association of Midlife Diet With Subsequent Risk for Dementia.JAMA. March 12， 2019.

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    2019-03-15 pcw106

    #痴呆风险#

    0

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    2019-03-15 ms6519009802973839

    #饮食模式#

    0

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    2019-03-14 15938038573红旗飘飘

    已学习

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    2019-03-13 junJUN

    老年人痴呆何药可用？？

    0

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