Sci Rep:下尿路症状/良性前列腺增生治疗中,α-受体阻滞剂处方方式研究

2018-09-08 AlexYang MedSci原创

最近,有研究人员在治疗患有BPH患者中,调查了α-受体阻滞剂在处方中的趋势情况,并且利用国家健康保险服务中的国家样本群体数据,关注了2002年到2013年处方方式的变化情况。研究包括了年龄大于50岁的65596名诊断为BPH的韩国男性,他们均从2002年到2013年之间的NHIS-NSC数据库中鉴定得到。研究人员分析了每一种α-受体阻滞剂的处方方式,并推算了首次处方后为期3年跟踪调查的持久率、转化

最近,有研究人员在治疗患有BPH患者中,调查了α-受体阻滞剂在处方中的趋势情况,并且利用国家健康保险服务中的国家样本群体数据,关注了2002年到2013年处方方式的变化情况。

研究包括了年龄大于50岁的65596名诊断为BPH的韩国男性,他们均从2002年到2013年之间的NHIS-NSC数据库中鉴定得到。研究人员分析了每一种α-受体阻滞剂的处方方式,并推算了首次处方后为期3年跟踪调查的持久率、转化率和收益率情况。研究发现,总共有28318名年龄大于50岁的男性(64.95±9.12)在首次α-受体阻滞剂的处方后的6个月内改变了医疗药物。与其他α-受体阻滞剂相比,坦索罗辛展现了最高的持久率。在那些改变到第二种α-受体阻滞剂的患者中,坦索罗辛自从2000年中期是最常见的 α1-受体阻滞剂处方药,这也与其自身最高的持久率和收益率一致。

最后,研究人员指出,这些数据能够反映患者在 α1-受体阻滞剂治疗BPH中的满意情况,并且决定终止和改变药物治疗方式主要是基于症状或者副作用的变化。

原始出处:

Hyong Woo Moon, Jong Hyup Yang, Jin Bong Choi et al. Prescription pattern of alpha-blockers for management of lower urinary tract symptoms/benign prostatic hyperplasia. Sci Rep. 05 Sep 2018.

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    2019-05-07 zhyy88
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