美国风湿病学会 2013 :及时有效的治疗可减少风湿性关节炎患者2年后的致残率

2013-10-30 佚名 睿医资讯

纽约新近一项研究指出,风湿性关节炎的治疗烟雾可大幅增加患者2年后关节损伤和发生残疾的可能性。相关研究结果将在10月28日圣地亚哥美国风湿病学会/美国风湿病卫生专业人员协会上发表。 “我们需要对风湿性关节炎的患者进行相关教育。一些患者因为害怕而延误治疗。他们并未把这一疾病记在心上,或不愿意开始药物治疗。一些患者仅采用非药物方法,但多数非药物疗法作用有限,”研究的主导者Bykerk博士说。 “不幸

纽约新近一项研究指出,风湿性关节炎的治疗烟雾可大幅增加患者2年后关节损伤和发生残疾的可能性。相关研究结果将在10月28日圣地亚哥美国风湿病学会/美国风湿病卫生专业人员协会上发表。

“我们需要对风湿性关节炎的患者进行相关教育。一些患者因为害怕而延误治疗。他们并未把这一疾病记在心上,或不愿意开始药物治疗。一些患者仅采用非药物方法,但多数非药物疗法作用有限,”研究的主导者Bykerk博士说。

“不幸的是,我见过太多患者接受有效治疗的时间过迟,一年后往往疗效不佳,会发生关节损伤,而这是可以避免的。患者关节的炎症反应持续越久,发生关节损伤的可能性就越大,而且这将影响到患者此后的关节功能。”

风湿性关节炎(RA)是一种系统性疾病,主要累及患者关节。符合现行标准的起始治疗方案为早期应用抗风湿药物,此类药物已被证实可有效减少RA相关的炎症反应。迄今为止,尚无设计良好的安慰剂对照临床试验证实其他药物和疗效较弱的方案对该病有效。

这项新型研究纳入了RA早期患者,并在6个月后将其分为疾病活动度降低组或未降低组。疾病活动度降低为病程早期的治疗目标,定义为关节疼痛、肿胀程度和其他炎性标志物明显减少。当在研究2年时对患者进行比较发现, 6个月时RA疾病活动度降低的患者,其2年时的关节功能更好。在对这一患者人群进行的相关研究中,达到6个月时RA病情完全缓解的患者,2年时的关节功能更好。

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