骨科

订阅

MedSci主页 / 所有栏目 / 骨科

J Pediatr Orthop：ADHA药物会降低骨密度？

2016-03-28 Seven L MedSci原创

ADHA骨密度儿童
关注

近期发表在J Pediatr Orthop的研究表明，服用与注意缺陷多动障碍症（ADHD）相关处方药物的儿童和青少年，其总股骨、股骨颈和腰椎的骨密度（BMD）降低。该研究纳入了5135名8-17岁的参与者，根据自我报告或监护人的报告处获取参与者处方药物的服用情况，根据药物使用情况将其分为药物使用足和非药物使用者，其中药物使用者包括ADHD相关药物和其他药物。此外，通过双能X线扫描获取参与者BMD情

近期发表在J Pediatr Orthop的研究表明，服用与注意缺陷多动障碍症（ADHD）相关处方药物的儿童和青少年，其总股骨、股骨颈和腰椎的骨密度（BMD）降低。

该研究纳入了5135名8-17岁的参与者，根据自我报告或监护人的报告处获取参与者处方药物的服用情况，根据药物使用情况将其分为药物使用足和非药物使用者，其中药物使用者包括ADHD相关药物和其他药物。此外，通过双能X线扫描获取参与者BMD情况。

研究数据显示，ADHD药物组与非药物组相比，总股骨和股骨颈BMD分别相差 -0.4855和-0.4671；对于腰椎，该值为-0.3947。此外，ADHD组和非药物组相比，BMD在骨质疏松症范围内的比例分别为38.3%和21.6%，两组间差异具有统计学意义。

研究者指出，因为ADHD相关药物可能具有潜在的骨健康风险，因此在使用时，医生和家长应该充分认识到这一风险。

原始出处：

Howard JT, et al. Preliminary Evidence of an Association Between ADHD Medications and Diminished Bone Health in Children and Adolescents.J Pediatr Orthop. 2016;doi:10.1097/BPO.0000000000000651.

Study links ADHD medication with lower BMD in children and adolescents.Healio.March 23, 2016

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1726062, encodeId=9a231e26062ea, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 31 00:13:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637302, encodeId=acc4163e302d3, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Nov 10 19:13:00 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74390, encodeId=fe83e43904f, content=这好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74391, encodeId=8a76e4391f0, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=)]
    2016-08-31 feather89

    #PE#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1726062, encodeId=9a231e26062ea, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 31 00:13:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637302, encodeId=acc4163e302d3, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Nov 10 19:13:00 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74390, encodeId=fe83e43904f, content=这好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74391, encodeId=8a76e4391f0, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=)]
    2016-11-10 ms9608593228839890

    #DIA#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1726062, encodeId=9a231e26062ea, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 31 00:13:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637302, encodeId=acc4163e302d3, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Nov 10 19:13:00 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74390, encodeId=fe83e43904f, content=这好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74391, encodeId=8a76e4391f0, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=)]
    2016-03-29 milkshark

    这好文章

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1726062, encodeId=9a231e26062ea, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Wed Aug 31 00:13:00 CST 2016, time=2016-08-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1637302, encodeId=acc4163e302d3, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Nov 10 19:13:00 CST 2016, time=2016-11-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74390, encodeId=fe83e43904f, content=这好文章, beContent=null, objectType=article, channel=null, level=null, likeNumber=158, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=74391, encodeId=8a76e4391f0, content=好好学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7cde98330, createdName=milkshark, createdTime=Tue Mar 29 06:52:00 CST 2016, time=2016-03-29, status=1, ipAttribution=)]
    2016-03-29 milkshark

    好好学习

    0