AJRCCM：CPAP不改变OSA,CVD共存的肾功能

2017-08-12 MedSci MedSci原创

根据7月25日发表在《美国呼吸与危重病医学杂志》上的一项研究，对于患有阻塞性睡眠呼吸暂停综合症(OSA)和心血管疾病的人来说，持续的正气道压力(CPAP)不会改变肾功能。阻塞性睡眠呼吸暂停(OSA)与肾功能受损有关，但OSA治疗是否会影响肾功能存在不确定性。为了探讨持续正气道压力(CPAP)对共同存在的OSA和心血管疾病患者肾功能的影响。澳大利亚弗林德斯大学的Kelly A. Loffler博士及

根据7月25日发表在《美国呼吸与危重病医学杂志》上的一项研究，对于患有阻塞性睡眠呼吸暂停综合症(OSA)和心血管疾病的人来说，持续的正气道压力(CPAP)不会改变肾功能。阻塞性睡眠呼吸暂停(OSA)与肾功能受损有关，但OSA治疗是否会影响肾功能存在不确定性。为了探讨持续正气道压力(CPAP)对共同存在的OSA和心血管疾病患者肾功能的影响。澳大利亚弗林德斯大学的Kelly A. Loffler博士及其同事在国际睡眠呼吸暂停和心血管终点试验的研究中检查了CPAP对并发OSA和心血管疾病个体的肾功能的影响。比较了102例CPAP治疗和98例常规治疗患者的肾功能及不良反应。研究人员发现，在4.4年的中位期后，CPAP和常规治疗组之间的肾小球滤过率的中值变化没有明显的差异。在研究后期检测尿白蛋白与肌酐比值或发生严重的肾或尿不良事件时，均无组间差异。研究结果不受CPAP粘附水平的影响。作者写道："CPAP治疗心血管疾病患者的OSA不会改变肾功能，也不会发生肾不良事件。"Respironics Sleep和Philips Respironics为试验提供资金支持。原文出处：Kelly A Loffl

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2018-02-01 isabellayj

#RCC#

26 0
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2017-09-22 yese

#肾功能#

21 0
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2017-11-23 ms1467340776200723

#PAP#

30 0
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2017-08-14 肉我只吃一口

#CPAP#

39 0
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2017-08-14 bioon3

#OSA#

34 0
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2017-08-12 1ddf0692m34(暂无匿称)

学习了，涨知识

65 0
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2017-08-12 中医痴

不错的，学习了，谢谢分享！

60 0
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2017-08-12 1e14ffd0m25(暂无匿称)

学习学习

73 0

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