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Ann Neurol：直立性低血压对2型糖尿病认知的影响

2019-08-12 xing.T MedSci原创

直立性低血压2型糖尿病认知
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这些数据表明，伴有OH的2型糖尿病患者具有短暂的、姿势介导的认知缺陷超过了不伴有OH的糖尿病患者发生的认知缺陷。了解OH对自主神经衰竭引起的认知影响很重要，特别是仅在坐位或仰卧位收集临床评估和神经影像学数据。

近日，神经病学领域权威取杂志Annals of Neurology上发表了一篇研究文章，该研究旨在评估符合直立性低血压（OH）诊断标准的血压降低（BP）对2型糖尿病患者认知功能的的影响。 

受试者为没有痴呆的2型糖尿病患者，包括107个没有OH的个体和94个具有OH（DMOH）的个体；还包括95名对照参与者。在仰卧和站立位置评估血压。对所有受试者进行详细的神经心理学评估。

DM和DMOH组之间在仰卧时的某些认知指标方面有统计学意义。对于不同认知领域的所有指标，包括执行功能、记忆、视觉空间技能、信息处理速度和注意力，站立姿势加剧并扩大了DMOH组的认知缺陷。当组特异性仰卧评分用作基线锚时，两个DM组在从仰卧位转变为直立位时表现出认知改变，DMOH组在记忆、视觉空间技能、执行功能和注意力方面表现出更广泛的神经心理缺陷，以及信息处理速度的也显著改变。

这些数据表明，伴有OH的2型糖尿病患者具有短暂的、姿势介导的认知缺陷超过了不伴有OH的糖尿病患者发生的认知缺陷。了解OH对自主神经衰竭引起的认知影响很重要，特别是仅在坐位或仰卧位收集临床评估和神经影像学数据。 

原始出处：

Jinbiao Zhang,et al.Effects of Orthostatic Hypotension on Cognition in Type 2 Diabetes Mellitus.Annals of Neurology. 2019.https://onlinelibrary.wiley.com/doi/10.1002/ana.25578

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    2019-09-30 yinhl1978

    #Neurol#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=2000841, encodeId=d0f820008417a, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Sep 30 10:32:00 CST 2019, time=2019-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367391, encodeId=d178136e391a4, content=<a href='/topic/show?id=f4012634656' target=_blank style='color:#2F92EE;'>#低血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26346, encryptionId=f4012634656, topicName=低血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Tue Aug 13 23:32:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422876, encodeId=151b14228e606, content=<a href='/topic/show?id=16d7e24580f' target=_blank style='color:#2F92EE;'>#直立性低血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72458, encryptionId=16d7e24580f, topicName=直立性低血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ab73741511, createdName=chaojitidian, createdTime=Tue Aug 13 23:32:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371197, encodeId=211c3e1197eb, content=血压和糖尿病之间关系密切。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Tue Aug 13 08:09:06 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042639, encodeId=30b310426396d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon Aug 12 11:32:00 CST 2019, time=2019-08-12, status=1, ipAttribution=)]
    2019-08-13 chentianping

    #低血压#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=2000841, encodeId=d0f820008417a, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Sep 30 10:32:00 CST 2019, time=2019-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367391, encodeId=d178136e391a4, content=<a href='/topic/show?id=f4012634656' target=_blank style='color:#2F92EE;'>#低血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26346, encryptionId=f4012634656, topicName=低血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Tue Aug 13 23:32:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422876, encodeId=151b14228e606, content=<a href='/topic/show?id=16d7e24580f' target=_blank style='color:#2F92EE;'>#直立性低血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72458, encryptionId=16d7e24580f, topicName=直立性低血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ab73741511, createdName=chaojitidian, createdTime=Tue Aug 13 23:32:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371197, encodeId=211c3e1197eb, content=血压和糖尿病之间关系密切。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Tue Aug 13 08:09:06 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042639, encodeId=30b310426396d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon Aug 12 11:32:00 CST 2019, time=2019-08-12, status=1, ipAttribution=)]
    2019-08-13 chaojitidian

    #直立性低血压#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2000841, encodeId=d0f820008417a, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Mon Sep 30 10:32:00 CST 2019, time=2019-09-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1367391, encodeId=d178136e391a4, content=<a href='/topic/show?id=f4012634656' target=_blank style='color:#2F92EE;'>#低血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26346, encryptionId=f4012634656, topicName=低血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f634250, createdName=chentianping, createdTime=Tue Aug 13 23:32:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422876, encodeId=151b14228e606, content=<a href='/topic/show?id=16d7e24580f' target=_blank style='color:#2F92EE;'>#直立性低血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72458, encryptionId=16d7e24580f, topicName=直立性低血压)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6ab73741511, createdName=chaojitidian, createdTime=Tue Aug 13 23:32:00 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371197, encodeId=211c3e1197eb, content=血压和糖尿病之间关系密切。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=00501987275, createdName=130****4638, createdTime=Tue Aug 13 08:09:06 CST 2019, time=2019-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1042639, encodeId=30b310426396d, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Mon Aug 12 11:32:00 CST 2019, time=2019-08-12, status=1, ipAttribution=)]
    2019-08-13 130****4638

    血压和糖尿病之间关系密切。

    0

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    2019-08-12 misszhang

    谢谢MedSci提供最新的资讯

    0

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