Stroke:预测急性缺血性卒中的早期死亡率的评分工具

2018-12-14 xing.T MedSci原创

由此可见,研究人员开发了一个简单的评分来评估在卒中单元接受治疗的缺血性卒中患者的早期死亡率。该评分可以帮助临床医生对管理决策和咨询进行短期预测。

已知若干危险因素会增加缺血性卒中患者的中期和长期死亡率。关于早期卒中死亡率预测因子的信息很少,但在临床实践中经常需要。近日,卒中领域权威杂志Stroke上发表了一篇研究文章,研究人员的目标是开发一种快速适用的工具,用于预测卒中单元的早期死亡率。

研究人员使用来自全国奥地利卒中单元登记处的数据和多变量正则化逻辑回归分析来确定与缺血性卒中患者早期(卒中后7天内)死亡率相关的人口统计学和临床变量。然后使用这些变量来开发预测缺血性卒中评分的早期死亡率,该评分通过自举和时间得以验证。

该研究总纳入77653名缺血性卒中患者进行分析(中位年龄为74岁,47%为女性)。卒中单元的死亡率为2%,死亡患者停留的中位数为3天。年龄、美国国立卫生研究院卒中量表衡量的卒中严重程度、卒中前功能障碍(改良Rankin量表>0)、既往心脏病、糖尿病、后循环卒中综合征和非腔隙性卒中原因与死亡率相关,并用于建立预测缺血性卒中的早期死亡评分,范围从0到12分。在推导队列中,评分的曲线下面积为0.879(95%CI为0.871-0.886),验证队列中为0.884(95%CI为0.863-0.905)。评分≥10的患者在卒中单元的第一天内死亡风险为35%(95%CI为28%-43%)。

由此可见,研究人员开发了一个简单的评分来评估在卒中单元接受治疗的缺血性卒中患者的早期死亡率。该评分可以帮助临床医生对管理决策和咨询进行短期预测。

原始出处:

Thomas Gattringer,et al.Predicting Early Mortality of Acute Ischemic Stroke Score-Based Approach.Stroke. 2018.https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022863

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    2018-12-14 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2018-12-14 flysky120

    卒中的死亡率的知识

    0

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    2018-12-14 flysky120

    卒中的死亡率的知识

    0

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