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骨髓增生异常综合征的治疗：ASTX727已获美国FDA的孤儿药物指定

2019-09-04 Allan MedSci原创

ASTX727骨髓增生异常综合征孤儿药物指定
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总部位于日本东京的Astex制药公司近日宣布，美国FDA已授予其ASTX727（固定剂量的cedazuridine和地西他滨）用于治疗骨髓增生异常综合征（MDS）和慢性粒单核细胞白血病（CMML）。

总部位于日本东京的Astex制药公司近日宣布，美国FDA已授予其ASTX727（固定剂量的cedazuridine和地西他滨）用于治疗骨髓增生异常综合征（MDS）和慢性粒单核细胞白血病（CMML）。这项指定得到了III期ASCERTAIN研究的支持，结果表明，ASTX727治疗中度和高度MDS或CMML患者，已达到主要终点。

FDA的孤儿药物指定旨在服务美国罕见疾病（少于200,000人）患者。这些药物在获准上市后可获得七年市场独占权，免除FDA申请费，临床试验的税收抵免和药物开发过程中的其他潜在援助。


原始出处：

http://www.firstwordpharma.com/node/1663640#axzz5yVqufGke

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    2020-05-03 ms6980045490879608

    #孤儿药物#

    0

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    2019-11-25 xinmeili

    #骨髓增生异常综合#

    0

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    2020-05-01 huangshifeng

    #骨髓增生异常#

    0

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    2020-04-30 12498b37m83暂无昵称

    #孤儿药物指定#

    0

  5. 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likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/12/20/dafb36f63f4241903de36c3d053babb8.jpg, createdBy=d367105945, createdName=Midas, createdTime=Thu Sep 05 07:06:39 CST 2019, time=2019-09-05, status=1, ipAttribution=)]
    2020-02-11 ms24272190615788285182

    #AST#

    0

  6. 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likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/12/20/dafb36f63f4241903de36c3d053babb8.jpg, createdBy=d367105945, createdName=Midas, createdTime=Thu Sep 05 07:06:39 CST 2019, time=2019-09-05, status=1, ipAttribution=)]
    2020-08-03 fengyqf

    #骨髓增生#

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Sep 06 08:16:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551444, encodeId=25a615514445a, content=<a href='/topic/show?id=5d84e9716c0' target=_blank style='color:#2F92EE;'>#美国FDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79716, encryptionId=5d84e9716c0, topicName=美国FDA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a46914191431, createdName=10518098zz, createdTime=Fri Sep 06 08:16:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372300, encodeId=2a653e230071, content=期待详细介绍啊，小编, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/12/20/dafb36f63f4241903de36c3d053babb8.jpg, createdBy=d367105945, createdName=Midas, createdTime=Thu Sep 05 07:06:39 CST 2019, time=2019-09-05, status=1, ipAttribution=)]
    2019-09-06 zhouqu_8

    #综合征#

    0

  8. 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style='color:#2F92EE;'>#骨髓增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101961, encryptionId=d1ba10196122, topicName=骨髓增生)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=fengyqf, createdTime=Mon Aug 03 12:16:00 CST 2020, time=2020-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431615, encodeId=c0a71431615ae, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Sep 06 08:16:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551444, encodeId=25a615514445a, content=<a href='/topic/show?id=5d84e9716c0' target=_blank style='color:#2F92EE;'>#美国FDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79716, encryptionId=5d84e9716c0, topicName=美国FDA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a46914191431, createdName=10518098zz, createdTime=Fri Sep 06 08:16:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372300, encodeId=2a653e230071, content=期待详细介绍啊，小编, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/12/20/dafb36f63f4241903de36c3d053babb8.jpg, createdBy=d367105945, createdName=Midas, createdTime=Thu Sep 05 07:06:39 CST 2019, time=2019-09-05, status=1, ipAttribution=)]
    2019-09-06 10518098zz

    #美国FDA#

    0

  9. 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style='color:#2F92EE;'>#骨髓增生#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=101961, encryptionId=d1ba10196122, topicName=骨髓增生)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=fengyqf, createdTime=Mon Aug 03 12:16:00 CST 2020, time=2020-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431615, encodeId=c0a71431615ae, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Sep 06 08:16:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1551444, encodeId=25a615514445a, content=<a href='/topic/show?id=5d84e9716c0' target=_blank style='color:#2F92EE;'>#美国FDA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79716, encryptionId=5d84e9716c0, topicName=美国FDA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a46914191431, createdName=10518098zz, createdTime=Fri Sep 06 08:16:00 CST 2019, time=2019-09-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372300, encodeId=2a653e230071, content=期待详细介绍啊，小编, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/12/20/dafb36f63f4241903de36c3d053babb8.jpg, createdBy=d367105945, createdName=Midas, createdTime=Thu Sep 05 07:06:39 CST 2019, time=2019-09-05, status=1, ipAttribution=)]
    2019-09-05 Midas

    期待详细介绍啊，小编

    0