J Intern Med:对于慢性肾病患者,严格控制血压可能使情况更糟糕!

2017-11-20 sunshine2015 来宝网

据“内科学杂志”10月16日在线发表的一项研究显示,控制血压(BP)可能对中度至进展期慢性肾病患者无益,甚至可能有害。

强化血压控制对慢性肾脏疾病没有好处】据“内科学杂志”10月16日在线发表的一项研究显示,控制血压(BP)可能对中度至进展期慢性肾病患者无益,甚至可能有害

来自加利福尼亚大学欧文医学中心的Yoshitsugu Obi博士及其同事对收缩压干预试验进行了事后分析,以确定在估计的肾小球滤过率(eGFR)下强化血压控制的风险。

研究人员发现,eGFR较低(P相关性= 0.019),强化治疗对心血管的益处减弱,而eGFR不改变对急性肾损伤(AK)的不良反应(P相关性= 0.179)。 eGFR <45 mL / min / 1.73 m2的891名受试者强化治疗并没有降低心血管预后风险(风险比[HR] 0.92,95%可信区间0.62-1.38),而增加了急性肾损伤的比率(风险比HR增加1.73 ; 95%置信区间,1.12至2.66)。

作者写道:“强化血压控制可能对中度至慢性肾脏病患者提供很少或根本没有益处,甚至是有害的。”

几位作者披露了与制药行业的财务关系。

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    2017-11-20 Chongyang Zhang

    签到学习了很多

    0

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