Sensors:新型传感器可灵敏检测低浓度多巴胺监测神经疾病的发生

2017-12-04 MedSci MedSci原创

目前,老年痴呆症、帕金森病等神经系统疾病已成为老年人的严重障碍性疾病,而监测这些神经疾病的有效方法之一是检测神经递质,如多巴胺。金属材料(如金、铂等)广泛用于电化学检测方法,然而,多巴胺低浓度下监测的低灵敏度和线性限制了这些材料的使用。为了克服这些局限性,本研究最近研发了一种用氧化石墨烯覆盖的银纳米粒子(SNP)修饰电极来检测多巴胺。本研究中,研究人员通过电化学沉积法首次使用SNPs和氧化石墨烯对

目前,老年痴呆症、帕金森病等神经系统疾病已成为老年人的严重障碍性疾病,而监测这些神经疾病的有效方法之一是检测神经递质,如多巴胺。金属材料(如金、铂等)广泛用于电化学检测方法,然而,多巴胺低浓度下监测的低灵敏度和线性限制了这些材料的使用。

为了克服这些局限性,本研究最近研发了一种用氧化石墨烯覆盖的银纳米粒子(SNP)修饰电极来检测多巴胺。

本研究中,研究人员通过电化学沉积法首次使用SNPs和氧化石墨烯对氧化铟锡(ITO)电极表面进行了改性。结果显示,与以前的生物传感器相比,新开发的生物传感器在低多巴胺浓度下也可显示较强的电化学信号。

综上所述,本研究结果表明,新开发的石墨烯氧化物覆盖的SNP修饰电极可用于在低多巴胺浓度下增强电化学信号来监测神经疾病。

原始出处:

Shin JW, Kim KJ, et al. Silver Nanoparticle Modified Electrode Covered by Graphene Oxide for the Enhanced Electrochemical Detection of Dopamine. Sensors (Basel). 2017 Nov 29;17(12). pii: E2771. doi: 10.3390/s17122771.

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    2018-06-21 hxj0117
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    2017-12-06 三生有幸9135

    学习一下谢谢分享

    0

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    2017-12-06 mjldent
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    2017-12-04 135****7952平儿

    学了........

    0

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    2017-12-04 三生有幸9135

    学习一下谢谢分享

    0

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