Clin Rheumatol:在原发性干燥综合征中,扩展的高频定力测定可用来听力损失的早期测定

2017-07-31 AlexYang MedSci原创

最近,有研究人员在原发性干燥综合征(pSS)病人中,利用扩展的高频听力测定方法评估了听力功能,并且将听力功能与疾病活动指数联系起来。研究人员在1年内,将所有诊断为pSS的病人招募到研究中。另外,参与研究的病人还进行了耳科学评估、扩展的高频听力测定、鼓室导抗图和ESSPRI规模评估。研究总共包含了63名病人(60名女性和3名男性),平均年龄为49.5±9.9岁,并且均患有pSS。研究发现,在非常高的

最近,有研究人员在原发性干燥综合征(pSS)病人中,利用扩展的高频听力测定方法评估了听力功能,并且将听力功能与疾病活动指数联系起来。

研究人员在1年内,将所有诊断为pSS的病人招募到研究中。另外,参与研究的病人还进行了耳科学评估、扩展的高频听力测定、鼓室导抗图和ESSPRI规模评估。研究总共包含了63名病人(60名女性和3名男性),平均年龄为49.5±9.9岁,并且均患有pSS。研究发现,在非常高的频率下(10000-16000Hz),两只耳朵中听力损失的流行度为95.3%(60名病人),并且,所有病人的听力损失是感官性的。在疾病活跃指数和听力阈值之间并没有显著的差异。另外,研究人员还招募了188名平均年龄为47.02±9.7岁的健康人群作为对照组。通过比较pSS病人和健康组听力阈值,研究人员发现在500Hz以上时,两组之间的听力阈值具有显著的差异。在pSS病人中,当频率高于4000Hz时,病人表现出感官性听力损失。另外,感官性听力损失在pSS病人中高度流行,尤其在高频情况下。最后,研究人员指出,感官性听力损失可以作为原发性干燥综合征的相关症状,并且还建议进行更为深入的研究来支持该结论。

原始出处:

González JLT, Torres JR, Ríos YH et al. Extended high-frequency audiometry as early detection of hearing loss in primary Sjögren syndrome. Clin Rheumatol. 26 Jul 2017.

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    2017-08-02 ysjykql
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最近,有研究人员利用增强磁共振(MRI)调查了内耳淋巴积液(EH)的存在在具有单边感官听力损失(SNHL)病人中受影响和不受影响耳朵中的情况,并且评估了EH在各种耳科疾病中的意义。该研究是一个回顾性的研究,并在大学医院里进行。研究包括了来自92名患有单边SNHL病人的182只耳朵。研究人员利用具有钆双胺一水物的3-特斯拉MRI对内淋巴空间进行评估。另外,他们还对耳蜗中和耳前庭中,EH程度的图片数据

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最近,有研究人员就耳蜗移植病人长期的病况表现进行了分析。研究采用回顾性的纵向研究,背景为具有一个大规模的耳蜗移植计划的三级转诊中心。另外,研究人员还对进行耳蜗移植病人在短期(1.12±0.15年)和长期(12.61±2.34年)时间后,在安静环境下和具有背景噪音环境下的言语感知得分进行了评估。研究包括了58只耳蜗移植的耳朵,这些耳朵来自于55名病人,病人的耳蜗移植时的平均年龄为51.80±1.75

Int Arch Otorhinolaryngol:突发性感官听力损失与自身免疫系统疾病

之前,有一些作者表述了突发性感官听力损失(SNHL)与系统性自身免疫疾病(SAD)的关系。免疫调节的SNHL很少的表现为单边突发SNHL,并且数年后在对侧耳中才表现出免疫调节的SNHL。鉴于早期和适当的治疗应用,免疫调节的SNHL作为少数可以逆转的SNHL之一,表现出了临床相关性。最近,有研究人员描述了患有先天突发性SNHL和SAD且与免疫调节SNHL可能性诊断相关病人的临床表现和听力学发现。更多