Gastroenterology:计算机辅助肠道息肉定性分析

2017-10-17 zhangfan MedSci原创

研究认为,对于体积小于5 mm息肉的良恶性区分,计算机辅助系统DNN-CAD表现出良好的检测效果,该系统将提高肠道息肉区分定性的准确性

窄带成像(NBI)是内镜图像的增强形式,可用于粘膜上皮和毛细血管显微结构观察,实时预测结直肠息肉的组织学特征,但NBI用于增生性息肉和肿瘤息肉的区分需要较高的专业性。近日研究人员考察了计算机辅助系统DNN-CAD用于NBI大肠息肉区分的准确性。

研究收集了1476例肿瘤性息肉和681例增生性息肉的影像作为组织学检查结果的参考标准,同时采集了96例增生性息肉以及188例肿瘤性息肉样本,样本息肉体积小于5mm,考察DNN-CAD系统以及内镜医生(2名专家,4名实习医生)对息肉检查结果的差异。研究的主要终点是诊断准确性、敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)和诊断时间。

研究发现,DNN-CAD对于增生性息肉和肿瘤息肉区分的敏感性为96.3%,特异性为78.1%,PPV为89.6%,NPV为91.5%。实习医生对于息肉诊断的NPV为73.9- 84.0%。DNN-CAD做出诊断的时间为0.45±0.07秒,显著优于专家的1.54±1.30秒以及实习医生的1.77±1.37秒

研究认为,对于体积小于5 mm息肉的良恶性区分,计算机辅助系统DNN-CAD表现出良好的检测效果,该系统将提高肠道息肉区分定性的准确性。

原始出处:

Peng-Jen Chen et al. Accurate Classification of Diminutive Colorectal Polyps Using Computer-aided Analysis. Gastroenterology. October 11, 2017.

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    2018-06-09 bioon14
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    2018-03-09 许安
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    2017-10-17 戒馋,懒,贪

    谢谢分享

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