JAHA:咖啡摄入量和冠状动脉钙化评分!

2018-03-25 xing.T MedSci原创

每天习惯性地摄入咖啡超过3杯降低了从不吸烟者亚临床动脉粥样硬化的几率。饮用咖啡对冠状动脉钙化有潜在的保护作用,特别是不吸烟者。

咖啡摄入量与亚临床动脉粥样硬化之间关系的现有证据比较有限且不一致。近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在探讨咖啡摄入量和冠状动脉钙化(CAC)之间的关联。

该横断面研究是基于埃尔莎‐巴西队列参与者的基线数据。只有生活中巴西圣保罗接受了CAC检查的参与者被纳入研究(n=4426)。研究人员使用食物频率问卷收集了参与者的咖啡摄入量。CAC采用CT进行检测,并以Agatston为单位。进一步以Agatson评分≥100(CAC≥100)对CAC进行分类。多因素logistic回归分析考虑了咖啡与吸烟之间的相互作用。

研究人员发现咖啡摄入量(>3杯/天)与CAC≥100之间存在显著的负相关性(≤1杯/天的比值比[OR]:0.85[95%可信区间为0.58–1.24];1–3杯/天的OR:0.73[95%可信区间0.51–1.05];超过3杯/天OR:0.33[95%可信区间0.17–0.65])。此外,咖啡摄入量和吸烟状况之间存在显著的相互作用(交互作用P=0.028)。根据吸烟状态进行分层后,分析显示不吸烟的咖啡摄入量>3杯/天的参与者冠状动脉钙化的比值比较低(OR:0.37[95%可信区间为0.15-0.91]),而在当前吸烟者和既往吸烟者中,咖啡摄入量与冠状动脉钙化之间没有显著的相关性。

由此可见,每天习惯性地摄入咖啡超过3杯降低了从不吸烟者亚临床动脉粥样硬化的几率。饮用咖啡对冠状动脉钙化有潜在的保护作用,特别是不吸烟者。

原始出处:

Andreia M. Miranda,et al. Coffee Consumption and Coronary Artery Calcium Score: Cross‐Sectional Results of ELSA‐Brasil (Brazilian Longitudinal Study of Adult Health).JAHA.2018. https://doi.org/10.1161/JAHA.117.007155

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    2019-03-04 lmm397
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  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Sun Mar 25 21:09:32 CST 2018, time=2018-03-25, status=1, ipAttribution=)]
    2018-03-27 zhaohui6731
  6. 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  7. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Sun Mar 25 21:09:32 CST 2018, time=2018-03-25, status=1, ipAttribution=)]
  8. [GetPortalCommentsPageByObjectIdResponse(id=1860624, encodeId=8f611860624e0, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Mon Mar 04 10:49:00 CST 2019, time=2019-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663281, encodeId=560416632815e, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, 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style='color:#2F92EE;'>#冠状动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30913, encryptionId=686830913f7, topicName=冠状动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Tue Mar 27 01:49:00 CST 2018, time=2018-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1511271, encodeId=433515112e1c6, content=<a href='/topic/show?id=d4ae3091531' target=_blank style='color:#2F92EE;'>#冠状动脉钙化评分#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30915, encryptionId=d4ae3091531, topicName=冠状动脉钙化评分)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=117e10313650, createdName=ms622625817193301, createdTime=Tue Mar 27 01:49:00 CST 2018, time=2018-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299808, encodeId=33e62998087b, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Mon Mar 26 07:48:13 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299745, encodeId=3f5e299e45a4, content=不错耶.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Mon Mar 26 07:08:11 CST 2018, time=2018-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=299627, encodeId=677a29962ea4, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Sun Mar 25 21:09:32 CST 2018, time=2018-03-25, status=1, ipAttribution=)]
    2018-03-26 yfjms

    学习

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1860624, encodeId=8f611860624e0, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Mon Mar 04 10:49:00 CST 2019, time=2019-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1663281, encodeId=560416632815e, content=<a href='/topic/show?id=4bae3334873' target=_blank style='color:#2F92EE;'>#动脉钙化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33348, encryptionId=4bae3334873, topicName=动脉钙化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3d1d25597695, 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Sun Mar 25 21:09:32 CST 2018, time=2018-03-25, status=1, ipAttribution=)]
    2018-03-26 owlhealth

    不错耶.学习了

    0

  10. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Sun Mar 25 21:09:32 CST 2018, time=2018-03-25, status=1, ipAttribution=)]
    2018-03-25 183****7028

    学习

    0

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