Eur Arch Otorhinolaryngol:突发性感官听力损失与白质病变有关系么?

2019-08-31 AlexYang MedSci原创

突发性感官听力损失(SSNHL)与血管病的病因具有相似处,比如心肌梗塞和脑卒中。因此,SSNHL可以作为血管疾病的早期迹象而不仅仅知识局部的疾病。大脑区域中的慢性低灌注能够导致慢性缺血损伤,称之为脑小血管病(CSVD),可以通过核磁共振(MRI)来进行检测。最近,有研究人员利用CSVD在SSNHL患者个体中鉴定了血管风险因素,并利用Fazekas评分量表对这些因素进行了鉴定。研究发现,与普通的人群

突发性感官听力损失(SSNHL)与血管病的病因具有相似处,比如心肌梗塞和脑卒中。因此,SSNHL可以作为血管疾病的早期迹象而不仅仅知识局部的疾病。大脑区域中的慢性低灌注能够导致慢性缺血损伤,称之为脑小血管病(CSVD),可以通过核磁共振(MRI)来进行检测。

最近,有研究人员利用CSVD在SSNHL患者个体中鉴定了血管风险因素,并利用Fazekas评分量表对这些因素进行了鉴定。研究发现,与普通的人群比较,年龄在48到60岁的SSNHL个体Fazekas评分高于1的可能性不小于26%。年龄小于28岁的个体与Fazekas评分高于0具有统计学显著的负相关关系。Fazekas评分越高,听力恢复的可能性就越低。听力恢复可能性中值为46%,且在Fazekas量表中,每增加一个分数,上述百分比就会减少16%。在他们的研究群体中,年龄小于48岁且Fazekas评分为0的个体听力恢复概率为80%,而Fazekas评分为3和4的个体中,听力恢复概率减少到了14%。

最后,研究人员指出,在年龄为48到60岁的SSNHL患者中,CSVD的患病率要比普通人群更高。更多的是,CSVD的存在于听力恢复可能性的减少有关,且在中风患者中已有阐释。

原始出处:

Fusconi M, Attanasio G, Capitani F et al. Is there a relation between sudden sensorineural hearing loss and white matter lesions? Eur Arch Otorhinolaryngol. 13 Aug 2019

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    2019-09-02 ysjykql
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    2019-08-31 phoebeyan520

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