Front Physiol:戒烟者注意:有香味的电子香烟是有毒的

2018-02-05 榕榕 译自MNT 来宝网

最近在“生理学前沿”杂志上发表的研究考察了电子烟蒸气对两种类型白血球的影响。研究结果表明,使电子香烟有味道的化合物是有毒的,有些味道比其他味道更差。

最近在“生理学前沿”杂志上发表的研究考察了电子烟蒸气对两种类型白血球的影响。研究结果表明,使电子香烟有味道的化合物是有毒的,有些味道比其他味道更差。

尽管电子烟(电子烟)帮助一些人戒烟,但还含有许多其他非尼古丁化学物质,其健康效应仍在研究之中。

一些研究表明,电子烟可能会对心血管造成不良影响,并且可能会降低心率。

这些研究中一部分是通过观察,还有一部分是在小鼠中进行实验,因此无法解释因果关系吸烟与对心血管影响的确切关系。

然而,纽约罗彻斯特大学医学中心的科学家开始试验假设——不含尼古丁的电子香烟比传统香烟危害小。

为此,由资深作者Irfan Rahman博士领导的研究人员将重点放在“这些电子烟调味化学品对两种人类单核细胞系的免疫毒理学和氧化应激效应”上。

氧化应激是氧自由基产生过量的过程,导致一系列的破坏作用,包括毒性增加,对DNA损伤甚至癌症。

单核细胞是一种在我们对炎症的免疫应答中起关键作用的白细胞。因此,新研究的结果对于我们理解电子香烟与我们的免疫系统之间的关系至关重要。

肉桂,香草,黄油味道最差

为了评估调味剂引起氧化应激的可能性,研究小组测量了所谓的活性氧(ROS)的产生。

作者写道:“我们假设,用于电子果汁/电子液体的调味化学品会诱导炎症反应,细胞毒性和ROS产生。

正如预期的那样,第一作者Thivanka Muthumalage博士及其同事进行的细胞毒性试验表明,用这些化学物质治疗会增加炎症和组织损伤。这些反应都是通过增加氧化应激水平来完成的。

另外,研究人员补充说:“混合多种口味与单独使用口味相比,具有更高的细胞毒性和无细胞ROS水平,这表明混合多种口味的电子液体对使用者的危害更大。

作者总结说:“我们的数据表明,电子果汁中使用的调味剂可以在单核细胞中引发炎症反应,由ROS产生介导,引发对电子香烟使用者潜在的肺毒性和组织损伤。”

“肉桂,香草和黄油调味化学品的毒性最大,但是我们的研究表明,混合风味的电子液体对白细胞毒性最大。”

--Thivanka Muthumalage博士

拉赫曼博士评论这些调查结果的意义,他说:“目前,[不含尼古丁的电子香烟],使用诱人的味道名称,如糖果,蛋糕,肉桂卷和神秘组合的味道的这类电子香烟吸引年轻的使用者。”

他补充说:“我们的科学研究结果表明,电子液体口味可以而且应该受到管制,电子液体的瓶子必须有所有成分的描述性列表。我们敦促管理机构采取行动保护公共健康。

原始出处:Thivanka Muthumalage, Melanie Prinz, Kwadwo O. Ansah, et al. Inflammatory and Oxidative Responses Induced by Exposure to Commonly Used e-Cigarette Flavoring Chemicals and Flavored e-Liquids without Nicotine.[J] Front. Physiol., 11 January 2018

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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Tue Feb 06 08:14:21 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285587, encodeId=9d5028558e71, content=学习学习.继续关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Tue Feb 06 08:07:46 CST 2018, time=2018-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285555, encodeId=3421285555f5, content=学习学习学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Feb 06 06:49:19 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
    2018-02-07 元元maple

    电子烟家人实验效果一般

    0

  5. 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  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Feb 06 06:49:19 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
    2018-02-06 1ddf0692m34(暂无匿称)

    学习了.涨知识

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Feb 06 06:49:19 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
    2018-02-06 明月清辉

    谢谢分享.学习了

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Feb 06 06:49:19 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
    2018-02-06 龙胆草

    学习谢谢分享

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRkia1DP5MpwEgtXo1XhXA11xD6MWKxunAZFXKSNic0fWHUQx83oNHPlRMxxIctM83QKeCLkJpMibibiaC/0, createdBy=7e581734408, createdName=深海的鱼, createdTime=Tue Feb 06 06:49:19 CST 2018, time=2018-02-06, status=1, ipAttribution=)]
    2018-02-06 1dd8c52fm63(暂无匿称)

    学习学习.继续关注

    0

  10. 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    2018-02-06 深海的鱼

    学习学习学习

    0

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一项新的研究表明,与普通香烟相比,电子香烟能够为人们带来相同含量的尼古丁,但电子烟中的毒素、致癌物质含量降低了。“这项研究表明:对吸烟者来说,完全停止接触普通香烟,投入电子香烟的怀抱,可能能够显着减少人体与很多致癌物质的接触机会,”该研究的作者 Maciej Goniewicz 表示,他是纽约布法罗罗斯威尔帕克癌症研究所肿瘤学助理教授。在该项研究中,研究者们招募了20名成年人,他们每天都会吸烟,并

PLOS ONE:电子烟同样会释放大量致癌物!

波特兰州立大学的研究人员发现当电子烟高功率运行时,其气化物中会形成大量的致癌物:苯。研究报告发表于 8 日的线上杂志《国家公共图书馆》中。

Sci Rep:电子烟和非电子烟使用者尿液中膀胱癌致癌物质比较

电子烟(EC)的使用的流行度越来越高,并且可以作为传统抽烟的替代品,原因是人们认为电子烟是一种更为安全的选择。与使用者认为ECs代表没有风险的观念不同,研究人员的起始研究阐释了电子烟液体中复杂的物质组成。传统的抽烟已被人们认识是膀胱癌发展的风险因子,并且先前的研究报道提醒了人们电子烟液体或者蒸汽中也许包括了那些引起膀胱癌发展的复合物。研究人员从13名电子烟使用者和10名非电子烟使用者中搜集了尿液样