J AAPOS:弱视儿童的OCT血管造影结果

2018-07-25 cuiguizhong MedSci原创

葡萄牙科英布拉大学中心眼科学系的Sobral I近日在J AAPOS发表一项重要工作,他们使用光学相干断层扫描血管造影术(OCT-A),比较了对侧眼儿童和健康儿童在弱视眼的微观结构和血管分布方面的差异。

葡萄牙科英布拉大学中心眼科学系的Sobral I近日在J AAPOS发表一项重要工作,他们使用光学相干断层扫描血管造影术(OCT-A),比较了对侧眼儿童和健康儿童在弱视眼的微观结构和血管分布方面的差异。

他们使用OCT-A(Avanti RTVue XR,Optovue Inc,Fremont,CA)对黄斑和视盘血管密度、流动面积等进行了前瞻性横断面研究,并使用自动化软件进行相关参数计算。

他们共纳入52名儿童,有26名弱视受试者和26名非弱视对照者。弱视眼受试者的浅表毛细血管丛(SCP)内的黄斑血管密度显着下降(P = 0.0171),在视盘流动面积(P = 0.0195)、平均的视网膜神经纤维层厚度(P = 0.0194)以及SCP黄斑血流面积(P = 0.0305)和视神经密度(P = 0.0279)等方面呈现轻微下降,具有统计学差异。在SCP的黄斑血管密度方面,弱视眼SCP的黄斑血流区域(P = 0.005)和深部毛细血管丛(DCP; P = 0.002)部位都比对照组有显着的下降(P = 0.022),在视盘流动面积(P = 0.004)和DCP中心凹无血管区域面积等方面略有增加(P = 0.038)。

因此,他们认为,在他们的研究队列中,弱视眼在黄斑和视盘血管化方面与健康对照组具有显着差异,这些发现的临床意义值得进一步研究。

原文出处:

Sobral, I., et al., OCT angiography findings in children with amblyopia. J aapos, 2018.

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    2019-04-29 habb
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    2019-05-25 ylz8410
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    2018-08-05 LSJ118
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    2018-07-27 sodoo
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    2018-07-26 1e1b8538m79(暂无匿称)

    不错的文章值得拥有哦

    0

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    2018-07-26 131****1460

    学习了受益匪浅

    0

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    2018-07-26 飛歌

    厉害了我的妹

    0

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    2018-07-25 清风拂面

    谢谢分享学习

    0

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