Br J Surg:胸主动脉瘤扩张率研究

2016-10-19 MedSci MedSci原创

所有胸主动脉瘤(TAA)患者必须强制性被监测。本研究的目的是,确定TAA的膨胀率和基于TAA直径的监视时间间隔。纳入有CT扫描形态数据的TAA患者,根据基线TAA直径和达到55 mm理论干预阈值时间,计算年化增长率。基于时间间隔为6 月,1年,2年和3年的模拟成像,发现将达到阈值,但还没有被发现的患者的数量。995例患者进行了2916次扫描,平均主动脉扩张速率为每年 2•76 mm, 45 mm以

所有胸主动脉瘤(TAA)患者必须强制性被监测。本研究的目的是,确定TAA的膨胀率和基于TAA直径的监视时间间隔。

纳入有CT扫描形态数据的TAA患者,根据基线TAA直径和达到55 mm理论干预阈值时间,计算年化增长率。基于时间间隔为6 月,1年,2年和3年的模拟成像,发现将达到阈值,但还没有被发现的患者的数量。

995例患者进行了2916次扫描,平均主动脉扩张速率为每年 2.76 mm, 45 mm以上后,呈指数增加。只有3.9%的初始直径为30-39 mm的患者和5.3%的初始直径为40-44 mm的患者,在2 年达到直径阈值。相反,初始直径为50-54 mm的患者,2年扩张到超过55 mm的概率是74.5%,3年概率是85.7%。

基于55 mm的干预阈值,大多数直径低于40 mm的患者可以2年监测一次。45 mm以上患者,建议每年监测。对于直径大于50 mm的患者,可以考虑手术治疗。

原始出处:

Patterson BO1, Sobocinski J2,3, Karthikesalingam A2, Hinchliffe RJ2, Loftus I2, Thompson MM2, Holt PJ2.Expansion rate of descending thoracic aortic aneurysms.Br J Surg. 2016 Oct 17. doi: 10.1002/bjs.10299. [Epub ahead of print]

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    2017-08-20 lsj637
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