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Stroke：非相关性脑动脉粥样硬化与急性脑梗塞患者神经转归不佳相关

2013-05-22 高晓方 译 医学论坛网

非相关性脑动脉粥样硬化急性脑梗塞患者神经转归
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　　韩国一项研究表明，在急性脑梗塞患者中，非相关性脑动脉粥样硬化（NRCA）与神经学转归不佳具有相关性。论文5月16日在线发表于《卒中》（Stroke）。 　　此项研究共纳入780例接受脑血管造影和弥散加权磁共振（MRI）检查的首发急性脑梗塞患者，并在伴和未伴NRCA的患者中对预后进行了对比。 　　结果显示，267例（34.2%）患者伴有NRCA。多变量分析显示，NRCA存在与前7日内NIH卒

　　韩国一项研究表明，在急性脑梗塞患者中，非相关性脑动脉粥样硬化（NRCA）与神经学转归不佳具有相关性。论文5月16日在线发表于《卒中》（Stroke）。

　　此项研究共纳入780例接受脑血管造影和弥散加权磁共振（MRI）检查的首发急性脑梗塞患者，并在伴和未伴NRCA的患者中对预后进行了对比。

　　结果显示，267例（34.2%）患者伴有NRCA。多变量分析显示，NRCA存在与前7日内NIH卒中评分改善较少独立相关（P=0.004  ），并于3个月后功能转归不佳（改良Rankin评分>2）独立相关[比值比（OR）2.51]。NRCA计数增加亦与不良转归相关。

Nonrelevant Cerebral Atherosclerosis is a Strong Prognostic Factor in Acute Cerebral Infarction
Background and Purpose
We investigated whether the presence of nonrelevant cerebral atherosclerosis (NRCA) had prognostic value in patients with acute stroke.
Methods
We compared prognosis in 780 consecutive patients with first-ever acute cerebral infarction who underwent cerebral angiography and diffusion-weighted MRI.
Results
NRCA was present in 267 patients (34.2%). Multivariate analysis demonstrated that the presence of NRCA was independently associated with less improvement in National Institute of Health Stroke Scale score during the first 7 days (P=0.004), and a poor functional outcome (modified Rankin Scale score >2) after 3 months (odds ratio, 2.51; 95% confidence interval, 1.55–4.07). An increase in burden count of NRCA was also associated with poor outcomes.
Conclusions
The presence and burden count of NRCA were associated with poor neurological outcomes in patients with acute cerebral infarction.    

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    2015-10-11 hlycom3356

    感谢作者分享

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    2013-09-02 yahu

    #脑动脉粥样硬化#

    0

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    2014-01-28 shenxlcyp

    #相关性#

    0

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    2013-09-14 respect

    #急性脑梗塞#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=38417, encodeId=9a6f3841eef, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 21:24:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1928882, encodeId=53031928882d0, content=<a href='/topic/show?id=dc1a84e431e' target=_blank style='color:#2F92EE;'>#脑动脉粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84743, encryptionId=dc1a84e431e, topicName=脑动脉粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Mon Sep 02 03:06:00 CST 2013, time=2013-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837116, encodeId=6de6183e116f0, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jan 28 17:06:00 CST 2014, time=2014-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1980710, encodeId=1f291980e1093, content=<a href='/topic/show?id=eeff52426d1' target=_blank style='color:#2F92EE;'>#急性脑梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52426, encryptionId=eeff52426d1, topicName=急性脑梗塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Sat Sep 14 13:06:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944348, encodeId=ffe619443485c, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Thu Aug 15 08:06:00 CST 2013, time=2013-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1312107, encodeId=70a0131210e57, content=<a href='/topic/show?id=750c848915d' target=_blank style='color:#2F92EE;'>#脑梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84891, encryptionId=750c848915d, topicName=脑梗塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Fri May 24 00:06:00 CST 2013, time=2013-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465042, encodeId=78f8146504272, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Fri May 24 00:06:00 CST 2013, time=2013-05-24, status=1, ipAttribution=)]
    2013-08-15 huangshifeng

    #粥样硬化#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=38417, encodeId=9a6f3841eef, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 21:24:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1928882, encodeId=53031928882d0, content=<a href='/topic/show?id=dc1a84e431e' target=_blank style='color:#2F92EE;'>#脑动脉粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84743, encryptionId=dc1a84e431e, topicName=脑动脉粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Mon Sep 02 03:06:00 CST 2013, time=2013-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837116, encodeId=6de6183e116f0, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jan 28 17:06:00 CST 2014, time=2014-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1980710, encodeId=1f291980e1093, content=<a href='/topic/show?id=eeff52426d1' target=_blank style='color:#2F92EE;'>#急性脑梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52426, encryptionId=eeff52426d1, topicName=急性脑梗塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Sat Sep 14 13:06:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944348, encodeId=ffe619443485c, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Thu Aug 15 08:06:00 CST 2013, time=2013-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1312107, encodeId=70a0131210e57, content=<a href='/topic/show?id=750c848915d' target=_blank style='color:#2F92EE;'>#脑梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84891, encryptionId=750c848915d, topicName=脑梗塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Fri May 24 00:06:00 CST 2013, time=2013-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465042, encodeId=78f8146504272, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Fri May 24 00:06:00 CST 2013, time=2013-05-24, status=1, ipAttribution=)]
    2013-05-24 huangshifeng

    #脑梗塞#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=38417, encodeId=9a6f3841eef, content=感谢作者分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=332823945, createdName=hlycom3356, createdTime=Sun Oct 11 21:24:00 CST 2015, time=2015-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1928882, encodeId=53031928882d0, content=<a href='/topic/show?id=dc1a84e431e' target=_blank style='color:#2F92EE;'>#脑动脉粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84743, encryptionId=dc1a84e431e, topicName=脑动脉粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=52c7237, createdName=yahu, createdTime=Mon Sep 02 03:06:00 CST 2013, time=2013-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1837116, encodeId=6de6183e116f0, content=<a href='/topic/show?id=3f34e253206' target=_blank style='color:#2F92EE;'>#相关性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72532, encryptionId=3f34e253206, topicName=相关性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Tue Jan 28 17:06:00 CST 2014, time=2014-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1980710, encodeId=1f291980e1093, content=<a href='/topic/show?id=eeff52426d1' target=_blank style='color:#2F92EE;'>#急性脑梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52426, encryptionId=eeff52426d1, topicName=急性脑梗塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8346212, createdName=respect, createdTime=Sat Sep 14 13:06:00 CST 2013, time=2013-09-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944348, encodeId=ffe619443485c, content=<a href='/topic/show?id=411de6300ad' target=_blank style='color:#2F92EE;'>#粥样硬化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76300, encryptionId=411de6300ad, topicName=粥样硬化)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Thu Aug 15 08:06:00 CST 2013, time=2013-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1312107, encodeId=70a0131210e57, content=<a href='/topic/show?id=750c848915d' target=_blank style='color:#2F92EE;'>#脑梗塞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84891, encryptionId=750c848915d, topicName=脑梗塞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b30d401, createdName=huangshifeng, createdTime=Fri May 24 00:06:00 CST 2013, time=2013-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1465042, encodeId=78f8146504272, content=<a href='/topic/show?id=2dea8489010' target=_blank style='color:#2F92EE;'>#脑梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84890, encryptionId=2dea8489010, topicName=脑梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccf56689148, createdName=karmond, createdTime=Fri May 24 00:06:00 CST 2013, time=2013-05-24, status=1, ipAttribution=)]
    2013-05-24 karmond

    #脑梗#

    0