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Neurology：美国神经病学学会(AAN)轻度认知障碍临床指南

2018-01-01 zhangfan MedSci原创

轻度认知障碍Ann运动
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美国神经病学学会(AAN)更新了公布于2001年的轻度认知障碍(MCI)指南

近日美国神经病学学会(AAN)更新了公布于2001年的轻度认知障碍(MCI)指南。

指导小组根据AAN证据分类标准，基于证据建议和修正的德尔菲共识，系统审查了MCI的患病率、预后和治疗方法相关研究以得出新的MCI治疗指南。

指南指出，各年龄段MCI发病率如下：60–64岁，6.7%；65–69岁，8.4%；70–74岁，10.1%；75–79岁，14.8%；80–84岁，25.2%。随访2年内，65岁以上人群累积的MCI发病率为14.9%。无有高质量的证据支持MCI的药物治疗。对于MCI患者，持续6个月以上的运动锻炼和认知训练有助于改善认知。

诊断及干预的主要建议如下：临床医生应在适当的情况下使用验证工具评估MCI(Level B)；临床医生应评估MCI患者的可变危险因素，功能损害以及治疗行为/神经精神症状(Level B)；临床医生应长期监测MCI患者认知状况(Level B)；在疑似MCI行为症状下，应停止认知损害药物(Level B)；临床医生应尽量减少胆碱酯酶抑制剂的使用(Level B)；在必需使用胆碱酯酶抑制剂的情况下，应首先进行证据讨论(Level A)；临床医生应建议患者进行定期运动(Level B)和认知训练(Level C)；临床医生应对患者及家属进行诊断、预后、长期治疗计划、缺乏有效医学干预手段(Level B)以及生物标志物(Level C)研究的交流。

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    2018-06-22 医者仁心

    #临床指南#

    0

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    2018-04-13 yinhl1978

    #Neurol#

    0

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    2018-02-04 122494370_76974194

    学习了受益匪浅

    0

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createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIt6X4iaHW8bDticcBSHUibNWk4Koe2icf0pdIOicSueicR3AKmviaSNPHkf9bCEicRK0anXEu3DjolU2EmkQ/132, createdBy=98ca5217513, createdName=bluefate123, createdTime=Wed Jan 03 00:36:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491297, encodeId=9509149129e6b, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Wed Jan 03 00:36:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274845, encodeId=7def2e4845b4, content=优质资源.共同学习, beContent=null, objectType=article, channel=null, level=null, 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content=谢谢学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jan 01 11:18:34 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-27 122494370_76974194

    优质资源学习一下

    0

  5. 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content=谢谢学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jan 01 11:18:34 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-04 虈亣靌

    学习了.涨知识了!

    0

  6. 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content=谢谢学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jan 01 11:18:34 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-03 bluefate123

    #AAN#

    0

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likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Jan 02 22:57:47 CST 2018, time=2018-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274488, encodeId=08172e4488be, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Mon Jan 01 14:04:38 CST 2018, time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274464, encodeId=8c3b2e446469, content=谢谢学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jan 01 11:18:34 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-03 axin012

    #神经病#

    0

  8. 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likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Jan 02 22:57:47 CST 2018, time=2018-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274488, encodeId=08172e4488be, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Mon Jan 01 14:04:38 CST 2018, time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274464, encodeId=8c3b2e446469, content=谢谢学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jan 01 11:18:34 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-02 虈亣靌

    优质资源.共同学习

    0

  9. 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createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIt6X4iaHW8bDticcBSHUibNWk4Koe2icf0pdIOicSueicR3AKmviaSNPHkf9bCEicRK0anXEu3DjolU2EmkQ/132, createdBy=98ca5217513, createdName=bluefate123, createdTime=Wed Jan 03 00:36:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1491297, encodeId=9509149129e6b, content=<a href='/topic/show?id=5316e4387aa' target=_blank style='color:#2F92EE;'>#神经病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74387, encryptionId=5316e4387aa, topicName=神经病)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=1ab48885684, createdName=axin012, createdTime=Wed Jan 03 00:36:00 CST 2018, time=2018-01-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274845, encodeId=7def2e4845b4, content=优质资源.共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Jan 02 22:57:47 CST 2018, time=2018-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274488, encodeId=08172e4488be, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Mon Jan 01 14:04:38 CST 2018, time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274464, encodeId=8c3b2e446469, content=谢谢学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jan 01 11:18:34 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-01 131****1460

    学习了受益匪浅

    0

  10. 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likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Jan 02 22:57:47 CST 2018, time=2018-01-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274488, encodeId=08172e4488be, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Mon Jan 01 14:04:38 CST 2018, time=2018-01-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=274464, encodeId=8c3b2e446469, content=谢谢学习一下知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Mon Jan 01 11:18:34 CST 2018, time=2018-01-01, status=1, ipAttribution=)]
    2018-01-01 flysky120

    谢谢学习一下知识了

    0

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