Asian Pac J Allergy Immunol:哮喘和/或过敏性鼻炎儿童中,大洪水和高空过敏症敏感性分析

2017-12-03 AlexYang MedSci原创

洪水也许能够影响气源性致敏原敏化。最近,有研究人员在泰国曼谷2011年大洪水前后,通过皮刺试验(SPT),进行了旨在评估患有哮喘和/或者过敏性鼻炎(AR)儿童气源性致敏原敏化情况的研究。研究分别在2009年和2013年,共在2010名哮喘和/或AR的儿童中进行了SPT试验,结果的阳性率分别为58.2%和60.5%。气源性致敏原的多敏化作用在SPT阳性病人中的67.5%的哮喘病人和67.0%的AR病

洪水也许能够影响气源性致敏原敏化。最近,有研究人员在泰国曼谷2011年大洪水前后,通过皮刺试验(SPT),进行了旨在评估患有哮喘和/或者过敏性鼻炎(AR)儿童气源性致敏原敏化情况的研究。

研究分别在2009年和2013年,共在2010名哮喘和/或AR的儿童中进行了SPT试验,结果的阳性率分别为58.2%和60.5%。气源性致敏原的多敏化作用在SPT阳性病人中的67.5%的哮喘病人和67.0%的AR病人中发现。在研究期间,屋尘螨(Dp)和粉尘螨(Df)是气源性致敏原敏感最为常见的起因(分别为82.4%和76.5%),其次为美洲蜚癆(43.5%)。在曼谷2011年严重的大洪水之后,对美洲蜚癆、百慕大草、约翰逊草和枝孢菌的敏化作用显著降低。然而,在2010年的研究案例中,对狗和交链孢霉过敏原的敏化作用趋势增加。另外,在研究期间,狗SPT的平均风团直径(MWD)与哮喘的严重度显著相关,然而Dp SPT的MWD与AR的严重度显著相关。

最后,研究人员指出,气源性致敏原敏化作用模式在洪水前后发生了变化。因此,大洪水也许对敏化类型和呼吸道过敏原的临床模式具有很大的影响。但是,同样需要前瞻性研究的进一步确定。

原始出处:

Visitsunthorn N, Chaimongkol W, Visitsunthorn K et al. Great flood and aeroallergen sensitization in children with asthma and/or allergic rhinitis. Asian Pac J Allergy Immunol. 22 Nov 2017.

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    2018-01-07 luwei00
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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM7GibvIBibibnnnvpajk2stlDF5oichYahI6Bia8uxeTBFoPbdoHWebyXf9eal9FNgUF2lNcrwoZicM3BvQ/0, createdBy=a3742066385, createdName=戒馋,懒,贪, createdTime=Sun Dec 03 12:47:14 CST 2017, time=2017-12-03, status=1, ipAttribution=)]
    2017-12-15 半夏微凉

    学习了谢谢分享

    0

  5. 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    2017-12-05 膀胱癌
  6. 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  7. 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  8. 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    2017-12-03 131****1460

    学习了受益匪浅

    0

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    2017-12-03 戒馋,懒,贪

    谢谢分享学习了

    0

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