Ophthal Plast Reconstr Surg:放射治疗后出现眼眶外结节边缘区淋巴瘤!

2018-01-12 cuiguizhong MedSci原创

哈佛医学院马萨诸塞州眼耳医院眼科的Tauqeer Z近日在Ophthal Plast Reconstr Surg杂志上发表了一项重要的工作,他们对2名眼眶外结节边缘区淋巴瘤发展超过十年的患者进行眼眶放射治疗,并研究这种辐射诱发的恶性肿瘤的可能性。

哈佛医学院马萨诸塞州眼耳医院眼科的Tauqeer Z近日在Ophthal Plast Reconstr Surg杂志上发表了一项重要的工作,他们对2名眼眶外结节边缘区淋巴瘤发展超过十年的患者进行眼眶放射治疗,并研究这种辐射诱发的恶性肿瘤的可能性。

他们对这2例病例进行回顾性病理学检查,并进行免疫组化染色等组织病理学检查。结果他们发现,第一名患者是58岁的女性。通过外束质子放射治疗颞下脉络膜黑色素瘤17年后,在外直肌附近出现眼眶周肿块。第二名患者是一名32岁的女性,通过光子放射治疗慢性炎性泪腺炎12年后,在右侧泪腺出现肿块。组织病理学和免疫组织化学研究证实,两例病例在眼眶外边缘区存在淋巴瘤。另外,对第二位患者的老年组织病理切片的回顾性分析显示,存在潜在的免疫球蛋白G4相关疾病。

这2例患者的不寻常的情况,提出了眼眶放射治疗是否会促进眼眶外结节边缘区淋巴瘤发展的问题。因此,他们认为,临床医生在评估眼眶肿块和以往局部放射治疗史时应考虑继发性恶性肿瘤的可能性。

原文出处:

Tauqeer, Z., et al., Orbital Extranodal Marginal Zone Lymphoma Following Radiotherapy: A Report of 2 Cases. Ophthal Plast Reconstr Surg, 2018.

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    2018-08-02 drj2003
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    2018-01-14 三生有幸9135

    学习一下谢谢分享

    0

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    2018-01-14 仁医06
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    2018-01-12 1e0e5697m83(暂无匿称)

    henhao

    0