Eur Radiol:内侧颞叶萎缩程度与认知功能有何相关性?与性别及教育程度又有什么关系呢?

2017-11-21 shaosai MedSci原创

本研究旨在确定不同颞叶萎缩(MTA)测量(左侧、右侧、平均及最高)的最佳截断值,同时将性别和教育程度纳入考虑当中,并探究其与认知功能的相关性,与5年内认知功能下降作比较,并将结果发表在Eur Radiol上。

本研究旨在确定不同颞叶萎缩(MTA)测量(左侧、右侧、平均及最高)的最佳截断值,同时将性别和教育程度纳入考虑当中,并探究其与认知功能的相关性,与5年内认知功能下降作比较,并将结果发表在Eur Radiol上。

本研究共纳入了390例75岁的老年人,并行磁共振成像检查及认知功能测试。利用Scheltens量表进行MTA评分(0-4)。5年后对278/390例患者再次进行认知功能测试。基于第10百分位数计算正常MTA最佳截断值。

结果为,大部分75岁老年人MTA评分≤2。男性评分要显着高于女性。在受过高等教育的人群中,左侧和平均MTA要明显高。异常MTA与认知功能测试结果较差具有相关性,右侧异常MTA认知功能下降更快。

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    2017-11-22 shaosai

    好好学习天天向上

    0