Clin Exp Rheumatol:超重和肥胖影响类风湿性关节炎中滑膜炎的临床评估

2018-07-22 xiangting MedSci原创

在高BMI的RA患者中,与超声相比,临床评估的SJC和DAS28都被低估了。

体重指数(BMI)可能会影响类风湿性关节炎(RA)的预后。由于肥胖相关的过量脂肪组织,肿胀关节计数(SJC)的临床评估也受到肥胖的影响。这项研究比较了超声检查(US)和临床检查在评估BMI对RA疾病活动性影响方面的区别。

这是一项单中心研究,纳入RA(ACR/EULAR标准)患者。US评估由一名不知道临床数据并受过训练的风湿病医师进行。US滑膜炎定义为灰度评分≥2和/或能量多普勒评分≥1。主要结局指标是临床和US评估(US临床检查)之间的SJC(ΔSJC)差异。次要结局是根据WHO分类,评估3个BMI亚组中临床和US评估间28关节疾病活动性评分(ΔDAS28)的差异。

纳入76名RA患者(平均年龄53.8±11.8岁;67%为女性)。总体而言,分别有28名(36.8%)、33名(43.4%)和15名(19.7%)患者为正常体重、超重和肥胖。3个BMI亚组间的基线特征没有差异。对于超重和肥胖RA患者,US确定的SJC显著高于临床确定的SJC:分别为p=0.001和p=0.049。仅在超重组内,US的DAS28高于临床检查(p=0.002)。单因素方差分析(ANOVA)显示3个BMI亚组间ΔDAS28存在显著差异(p=0.046)。

在高BMI的RA患者中,与超声相比,临床评估的SJC和DAS28都被低估了。

原始出处:

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1740902, encodeId=faff1e40902c4, content=<a href='/topic/show?id=9c76230166d' target=_blank style='color:#2F92EE;'>#临床评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23016, encryptionId=9c76230166d, topicName=临床评估)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e55d34837992, createdName=12498dabm88暂无昵称, createdTime=Mon Feb 04 09:27:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265763, encodeId=10791265e638a, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334053, encodeId=90cb13340536e, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379495, encodeId=f56613e949588, content=<a href='/topic/show?id=09e46655974' target=_blank style='color:#2F92EE;'>#滑膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66559, encryptionId=09e46655974, topicName=滑膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a98f453, createdName=pcw106, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483528, encodeId=f33c1483528bb, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333427, encodeId=165033342e99, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sun Jul 22 19:07:10 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1740902, encodeId=faff1e40902c4, content=<a href='/topic/show?id=9c76230166d' target=_blank style='color:#2F92EE;'>#临床评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23016, encryptionId=9c76230166d, topicName=临床评估)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e55d34837992, createdName=12498dabm88暂无昵称, createdTime=Mon Feb 04 09:27:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265763, encodeId=10791265e638a, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334053, encodeId=90cb13340536e, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379495, encodeId=f56613e949588, content=<a href='/topic/show?id=09e46655974' target=_blank style='color:#2F92EE;'>#滑膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66559, encryptionId=09e46655974, topicName=滑膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a98f453, createdName=pcw106, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483528, encodeId=f33c1483528bb, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333427, encodeId=165033342e99, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sun Jul 22 19:07:10 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
    2018-07-24 lmm397
  3. [GetPortalCommentsPageByObjectIdResponse(id=1740902, encodeId=faff1e40902c4, content=<a href='/topic/show?id=9c76230166d' target=_blank style='color:#2F92EE;'>#临床评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23016, encryptionId=9c76230166d, topicName=临床评估)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e55d34837992, createdName=12498dabm88暂无昵称, createdTime=Mon Feb 04 09:27:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265763, encodeId=10791265e638a, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334053, encodeId=90cb13340536e, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379495, encodeId=f56613e949588, content=<a href='/topic/show?id=09e46655974' target=_blank style='color:#2F92EE;'>#滑膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66559, encryptionId=09e46655974, topicName=滑膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a98f453, createdName=pcw106, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483528, encodeId=f33c1483528bb, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333427, encodeId=165033342e99, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sun Jul 22 19:07:10 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1740902, encodeId=faff1e40902c4, content=<a href='/topic/show?id=9c76230166d' target=_blank style='color:#2F92EE;'>#临床评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23016, encryptionId=9c76230166d, topicName=临床评估)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e55d34837992, createdName=12498dabm88暂无昵称, createdTime=Mon Feb 04 09:27:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265763, encodeId=10791265e638a, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334053, encodeId=90cb13340536e, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379495, encodeId=f56613e949588, content=<a href='/topic/show?id=09e46655974' target=_blank style='color:#2F92EE;'>#滑膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66559, encryptionId=09e46655974, topicName=滑膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a98f453, createdName=pcw106, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483528, encodeId=f33c1483528bb, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333427, encodeId=165033342e99, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sun Jul 22 19:07:10 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
    2018-07-24 pcw106
  5. [GetPortalCommentsPageByObjectIdResponse(id=1740902, encodeId=faff1e40902c4, content=<a href='/topic/show?id=9c76230166d' target=_blank style='color:#2F92EE;'>#临床评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23016, encryptionId=9c76230166d, topicName=临床评估)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e55d34837992, createdName=12498dabm88暂无昵称, createdTime=Mon Feb 04 09:27:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265763, encodeId=10791265e638a, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334053, encodeId=90cb13340536e, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379495, encodeId=f56613e949588, content=<a href='/topic/show?id=09e46655974' target=_blank style='color:#2F92EE;'>#滑膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66559, encryptionId=09e46655974, topicName=滑膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a98f453, createdName=pcw106, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483528, encodeId=f33c1483528bb, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333427, encodeId=165033342e99, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sun Jul 22 19:07:10 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1740902, encodeId=faff1e40902c4, content=<a href='/topic/show?id=9c76230166d' target=_blank style='color:#2F92EE;'>#临床评估#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23016, encryptionId=9c76230166d, topicName=临床评估)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e55d34837992, createdName=12498dabm88暂无昵称, createdTime=Mon Feb 04 09:27:00 CST 2019, time=2019-02-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265763, encodeId=10791265e638a, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1334053, encodeId=90cb13340536e, content=<a href='/topic/show?id=5306e6164b6' target=_blank style='color:#2F92EE;'>#类风湿#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76164, encryptionId=5306e6164b6, topicName=类风湿)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq2AGzrugK9ZUjU3eJxzM901ophWib0xJDrSicy49ibWl3zB5pbDto7eoR6tnzwOiaKdbq1a8PcbYFFrw/132, createdBy=6ff22500098, createdName=ms4964546379600229, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1379495, encodeId=f56613e949588, content=<a href='/topic/show?id=09e46655974' target=_blank style='color:#2F92EE;'>#滑膜炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=66559, encryptionId=09e46655974, topicName=滑膜炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a98f453, createdName=pcw106, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1483528, encodeId=f33c1483528bb, content=<a href='/topic/show?id=55a6100826cc' target=_blank style='color:#2F92EE;'>#风湿性关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100826, encryptionId=55a6100826cc, topicName=风湿性关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c237911872, createdName=ms1467340776200723, createdTime=Tue Jul 24 07:27:00 CST 2018, time=2018-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=333427, encodeId=165033342e99, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sun Jul 22 19:07:10 CST 2018, time=2018-07-22, status=1, ipAttribution=)]
    2018-07-22 张新亮1853311252142e2fm

    好文献学习了

    0

相关资讯

Ann Rheum Dis:类风湿性关节炎中的bDMARD难治性疾病

这项首例全国性研究确定了bDMARD难治性疾病的发生率至少为接受bDMARD治疗患者的6%。

J Rheumatol:妊娠期暴露于TNFi的母亲和胎儿结局

与妊娠期持续TNFi治疗的患者相比,妊娠期TNFi停药的女性围产期或产后急性发作的风险更高。

2018 多学科建议:类风湿性关节炎患者足部问题的诊断和治疗

类风湿性关节炎患者足部问题非常普遍,对生活质量造成重大影响。本文主要针对类风湿性关节炎患者足部问题的诊断和治疗提出指导建议,全文共提出41条指导建议,涉及诊治框架,足部护理,诊断,治疗等。

Arthritis Rheumatol:类风湿性关节炎中持续性克隆T-LGL扩增的患病率及特征

长期暴露于TNFα阻断剂的RA患者出现大颗粒淋巴细胞克隆性扩张的风险更高。

J Rheumatol:类风湿性关节炎中的心血管疾病预防

尽管CVD和糖尿病的风险较高,RA中对一般人群糖尿病筛查指南的依从性欠佳。

PLos One:类风湿性关节炎患者内镜下胃黏膜损伤的患病率

PSL和NSAIDs是胃粘膜损伤的加剧因素,而使用PPIs是保护性因素。并且,联合使用糖皮质激素和NSAIDs可能诱发胃溃疡。