JAHA:74项研究300多万人分析:睡太多比睡眠不足更有害!每晚睡7~8小时死亡风险很低

2018-08-13 朱柳媛 中国循环杂志

近日一项汇总了74项研究结果、覆盖超过334万人的分析结果表明,睡眠时间与死亡和心血管病发生风险之间均呈J型曲线关系,每晚睡7~8小时风险最低。

睡眠不足影响身体健康,比如会导致心脏代谢性疾病风险增加,这是众所周知的事情。然而,睡得太多也不是好事,而且睡太多的危害可能比睡眠不足还大!

近日一项汇总了74项研究结果、覆盖超过334万人的分析结果表明,睡眠时间与死亡和血管病发生风险之间均呈J型曲线关系,每晚睡7~8小时风险最低。

睡眠时间与死亡风险之间的关系

研究者发现,每晚睡眠不足7小时与死亡或血管病风险并无明确关联。

然而,睡眠超过8小时“可能有中度害处”。睡眠时间越长,风险越高。比如,每晚睡9小时,死亡风险增加14%;每晚睡10小时,死亡风险则增加30%;睡眠超过11小时,死亡风险会增加47%。

美国睡眠基金会建议,18~64岁人群每晚睡眠7~9小时,65岁以上人群每晚睡7~8小时。

当然,睡眠质量也同样影响身体健康。该研究显示,睡眠质量差的人发生冠心病的风险增加44%。

该研究的主要研究者、来自英国基尔大学的ChunShing Kwok指出,这项研究对公共卫生有重要的影响,因为“它提示睡眠过度是心血管风险增加的一个标志物”。

研究者还指出,这项研究首次发现,睡眠质量是冠心病的危险因素之一。因此,他们建议医生在评估患者的冠心病风险时应考虑其是否有“非复苏睡眠(醒来后并没有神清气爽的感觉)”。

作者表示,既往很多研究都评估了睡眠时间与死亡和心血管病风险之间的关系,但并没有探索睡眠时间每增加或减少1小时对身体的影响。同样,也没有研究评估睡眠质量的危害。

至于睡眠时间、睡眠质量和心血管病及死亡之间关联的具体机制,目前仍不是十分清楚。

有研究发现,睡眠不足会导致瘦素和生长激素释放肽等可以增强食欲、促进肠运动的激素水平升高,从而引发肥胖和糖代谢异常等问题,同时也会诱发炎症反应,而后者与心血管病关系密切。

睡眠过多则可能意味着本身存在慢性炎症或贫血等会使身体乏力的状况。另外,缺乏运动、抑郁、失业和社会经济状态较低也与睡眠过多有关。这些因素都与心血管病和死亡有关。

在现代社会,睡眠受文化、社会、心理、行为、病生理和环境等多重因素影响,比如,带娃、照顾年迈父母、倒班、精神和躯体疾病,等等。

原始出处:Chun Shing Kwok, Evangelos Kontopantelis, George Kuligowski, et al. Self‐Reported Sleep Duration and Quality and Cardiovascular Disease and Mortality: A Dose‐Response Meta‐Analysis. JAHA. 3 Aug 2018

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    2018-08-15 sillywu

    我的睡眠时间够,但是睡眠的时间段也很重要,最近掉头发

    0

  2. 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    2018-08-14 zhaohui6731
  3. 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  4. 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    2018-08-14 神功盖世

    学习

    0

  5. 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    2018-08-14 sunfeifeiyang

    学习

    0

  6. 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objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Mon Aug 13 10:45:38 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338316, encodeId=8acd33831680, content=看来要11点睡觉了, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/03/19/68358be9323aa8e32edd53bfd17742f1.jpg, createdBy=5a191960665, createdName=1e135751m36(暂无匿称), createdTime=Mon Aug 13 10:12:45 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338314, encodeId=28b6338314ee, content=优质资源,共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0LqDY57Aia0TOQByoJhNt3icm4sfukp500hLH6RHOpFdV01NbECtAV7s0qKpQPibyRukQAwAmqJU3X/0, createdBy=f91f1928792, createdName=九九消寒, createdTime=Mon Aug 13 09:24:19 CST 2018, time=2018-08-13, status=1, ipAttribution=)]
    2018-08-14 润泽River

    可以早睡,可以早起

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/fhZdOu27e88Voqh19n8eF8cLplo8L4nicKtH0WnE3KFELXns5XDu8rsiceK2HHDZc2SEStia5VV3Pia2QLMVqlWbHw/0, createdBy=6e012139475, createdName=神功盖世, createdTime=Tue Aug 14 10:31:54 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338523, encodeId=5d1a33852388, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/07/a9772c74ffd6edc03a7f9af07b4747f6.jpg, createdBy=b3722138742, createdName=sunfeifeiyang, createdTime=Tue Aug 14 10:30:20 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338499, encodeId=8441338499a3, content=可以早睡,可以早起, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TNV5cElot3tDNlyIMGic8HtYGcKD9cIvZR1TXRasIwjyib9BdYd3p4jcM75yvkr22FDhd6jseJmBOLaGyejic1vew/132, createdBy=fc402371135, createdName=润泽River, createdTime=Tue Aug 14 09:10:20 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338484, encodeId=5e8c3384844e, content=剂量反应meta, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eiadcQaiaZ4fUvicZKEbibPBA2otZ0yzMeAVET5icsaS77W0Tvo3ibFMibzxTVRPsg62xJu0GicwBCvAlPMyu7TB6j86ug/132, createdBy=d64c1981665, createdName=一一一多, createdTime=Tue Aug 14 08:15:22 CST 2018, time=2018-08-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338322, encodeId=0d323383224c, content=学习学习很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Mon Aug 13 10:45:38 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338316, encodeId=8acd33831680, content=看来要11点睡觉了, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/03/19/68358be9323aa8e32edd53bfd17742f1.jpg, createdBy=5a191960665, createdName=1e135751m36(暂无匿称), createdTime=Mon Aug 13 10:12:45 CST 2018, time=2018-08-13, status=1, ipAttribution=), 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    2018-08-14 一一一多

    剂量反应meta

    0

  8. 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objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Mon Aug 13 10:45:38 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338316, encodeId=8acd33831680, content=看来要11点睡觉了, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/03/19/68358be9323aa8e32edd53bfd17742f1.jpg, createdBy=5a191960665, createdName=1e135751m36(暂无匿称), createdTime=Mon Aug 13 10:12:45 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338314, encodeId=28b6338314ee, content=优质资源,共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0LqDY57Aia0TOQByoJhNt3icm4sfukp500hLH6RHOpFdV01NbECtAV7s0qKpQPibyRukQAwAmqJU3X/0, createdBy=f91f1928792, createdName=九九消寒, createdTime=Mon Aug 13 09:24:19 CST 2018, time=2018-08-13, status=1, ipAttribution=)]
    2018-08-13 易水河

    学习学习很好

    0

  9. 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objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTKibA62IFMeUJEmSyIe8DvYFeERuOsfrRd8iano7nENqQU1dRR3tqeQOUL3eqgYgEZRT2t2iaEsib0JEw/132, createdBy=66771693911, createdName=易水河, createdTime=Mon Aug 13 10:45:38 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338316, encodeId=8acd33831680, content=看来要11点睡觉了, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/03/19/68358be9323aa8e32edd53bfd17742f1.jpg, createdBy=5a191960665, createdName=1e135751m36(暂无匿称), createdTime=Mon Aug 13 10:12:45 CST 2018, time=2018-08-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338314, encodeId=28b6338314ee, content=优质资源,共同学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K0LqDY57Aia0TOQByoJhNt3icm4sfukp500hLH6RHOpFdV01NbECtAV7s0qKpQPibyRukQAwAmqJU3X/0, createdBy=f91f1928792, createdName=九九消寒, createdTime=Mon Aug 13 09:24:19 CST 2018, time=2018-08-13, status=1, ipAttribution=)]
    2018-08-13 1e135751m36(暂无匿称)

    看来要11点睡觉了

    0

  10. 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    2018-08-13 九九消寒

    优质资源,共同学习

    0

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