Am J Gastroenterol:上消化道出血症状与疾病程度及预后

2018-02-09 zhangfan MedSci原创

研究认为,对于上消化道出血患者,咖啡色呕吐症状预后较呕血差,呕血伴黑便患者的预后效果最差

一般认为对于上消化道出血的患者呕血症状的严重程度要高于咖啡色呕吐。近日研究人员开展前瞻性研究考察呕吐性状与疾病严重程度及结果的影响。

因吐血或黑便就诊患者参与研究,其中呕血患者1209名,咖啡色呕吐患者701人,吐血黑便患者1069人。研究人员考察了出血严重程度并对患者进行预后预测。研究的主要终点为输血、干预或死亡的复合终点。

研究发现,呕血以及咖啡色呕吐患者心率超过100(35 vs. 37%)、动脉压低于100mmHg(12 vs.12%)以及血红蛋白低于100g/l(25 vs 27%)的比例相近。呕血患者的风险评估得分较低,呕血vs咖啡色呕吐患者复合终点发生率分别为34.7%和38.2%,死亡率分别为6.6%和9.3%,止血干预率分别为19.4%和14.4%,再出血率分别为7.8%和4.5%。呕血伴黑便患者相对于单纯呕血以及咖啡色呕吐患者预后较差。

研究认为,对于上消化道出血患者,咖啡色呕吐症状预后较呕血差,呕血伴黑便患者的预后效果最差。

原始出处:


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    2021-01-20 气球小姐

    临床症状,呕血

    0

  2. 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    2018-11-07 许安
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beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Sat Feb 10 07:47:05 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
    2018-02-15 大爰

    学习了谢谢分享!!

    0

  6. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Sat Feb 10 07:47:05 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
    2018-02-13 爱吃鱼的菜

    学习了.谢谢分享

    0

  8. 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  9. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/TDiaAWyicHgedzX3wKo3qcxudVJib7AfibfvNeufHRF2jG3Bw8MmZyWjIhtBV1mpJI7Sy9n7RcBKK5t3CuOKuOFxkg/0, createdBy=dd702206933, createdName=wzb521zf, createdTime=Sat Feb 10 07:47:05 CST 2018, time=2018-02-10, status=1, ipAttribution=)]
    2018-02-10 半夏微凉

    学习了谢谢分享

    0

  10. 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    2018-02-10 wzb521zf

    一起学习学习

    0

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Glasgow Blatchford评分在预测以医院为基础的干预和死亡率方面具有较高的预测精度。其评分≤1分是引导患者门诊就诊的的最佳阈值。对于其他终点这些评分的AUROCS均低于0.80,因此这些结果的临床效用较为有限。

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1.上消化道出血量估计5-10ml  大便隐血(+)60-100ml  黑粪250-300ml  呕血<400ml  可代偿无症状700-800ml   全身乏力、眩晕口渴、畏寒、血压下降1500ml以上  出血性休克、烦躁不安、意识不清、面色苍白、四肢湿冷、口渴冷汗、血压下降(收<80mmHg),脉压<30mmHg 脉

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研究发现,非静脉曲张上消化道出血患者周末急诊的死亡风险高于静脉曲张上消化道出血患者,如何保证非工作日的医疗效果仍是一个重要的课题

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具有口服抗凝持续指征的患者中,上消化道(GI)出血后重新维生素K拮抗剂(VKAs)的最佳给药时机还不确定。2017年2月,发表在《Thromb Haemost》的一项风险模型分析调查了上消化道出血后重新VKA的最佳给药时机。请看本期多学科讨论组临床药师各抒己见为您梳理本文看点——研究人员从3家医院中回顾性纳入了VKA相关上GI出血的连续病例。研究人员收集了出血位置、重新开始VKA的时间、GI出血复