JACC:经导管主动脉瓣置换术后因心衰再入院的发生率、预后影响及预测因素

2017-12-10 xiangting MedSci原创

TAVR后因CHF再入院很常见,并与1年死亡率密切相关。

这项研究的目的是评估经导管主动脉瓣置换术(TAVR)治疗的重度主动脉瓣狭窄患者因充血性心力衰竭(CHF)再入院的发生率、预后影响和预测因素。

TAVR适用于重度症状性主动脉瓣狭窄患者,对于这类患者手术被认为是高风险或禁忌症。TAVR后因CHF再入院仍然是一个挑战,尚缺乏预后和预测因素的数据。

研究纳入2010年1月至2014年12月接受TAVR治疗的所有患者。随访至少1年,包括临床和超声心动图数据。对因CHF再入院进行回顾性分析。

这项研究共纳入546例患者,其中534例(97.8%)植入球囊扩张瓣膜,其中87.8%的患者中优先经股动脉通路。1年后,285例(52.2%)患者再入院至少一次,132例(24.1%)因CHF入院。因CHF再入院患者的死亡风险(p <0.0001)和心源性死亡风险(p <0.0001)高于不因CHF再入院的患者。多变量分析显示,主动脉平均梯度(危险比[HR]:0.88; 95%置信区间[CI]:0.79-0.99; p = 0.03),术后输血量(HR:2.27; 95%CI:1.13-5.56 ; P = 0.009),重度术后肺动脉高压(HR:1.04,95%CI:1.00-1.07; p <0.0001)和左心房直径(HR:1.47; 95%CI:1.08-2.01; p = 0.02 )与1年时的CHF再入院独立相关。

TAVR后因CHF再入院很常见,并与1年死亡率密切相关。低梯度,持续性肺动脉高压,左房扩大和输血是预测因CHF再入院的指标。

原始出处:

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    2018-10-28 hbwxf
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    2018-01-03 1e127dd4m40(暂无匿称)

    学习了

    0

  4. 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  5. 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  6. 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  7. 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    2017-12-12 lsj631

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EUR HEART J :基于心脏损伤程度的新型主动脉狭窄分期分级法

在主动脉瓣狭窄患者中,主动脉瓣置换术(AVR)的风险分级主要依赖于与瓣膜相关的因素、症状和复发病变。近日,在医学权威杂志EUR HEART J 上面发表了一篇研究文章,该文章旨在评估一种新定义的主动脉狭窄分期分级,该分级描述了在接受AVR治疗的主动脉瓣狭窄患者中,严重的主动脉瓣膜相关的心脏损伤程度及AVR预后影响。

EUR HEART J:肥胖与主动脉瓣狭窄发病率有关系吗?

近日,在医学权威杂志EUR HEART J 上面发表了一篇研究文章,研究人员旨在研究整体肥胖和腹部肥胖相关的主动脉瓣狭窄(AVS)发病率。