Cent Eur J Immunol:慢性牙周炎和侵袭性牙周炎患者龈沟液中MMP-8和IL-1β的浓度

2018-03-01 MedSci MedSci原创

研究已证实炎症介质在牙周组织破坏的病理机制中的作用。本研究旨在确定晚期慢性和侵袭性牙周炎患者龈沟液(GCF)中MMP-8和IL-1β的浓度。研究人员测量了33例晚期慢性牙周炎患者和16例侵袭性牙周炎患者的深牙周袋(PD≥6 mm)和浅牙周袋(PD 4-5 mm)的龈沟液中上述炎症介质的浓度。对照组由16名健康牙周组织组成。在所有患者中,用ELISA方法测定GCF中MMP-8和IL-1β的水平。结果

研究已证实炎症介质在牙周组织破坏的病理机制中的作用。本研究旨在确定晚期慢性和侵袭性牙周炎患者龈沟液(GCF)中MMP-8和IL-1β的浓度。

研究人员测量了33例晚期慢性牙周炎患者和16例侵袭性牙周炎患者的深牙周袋(PD≥6 mm)和浅牙周袋(PD 4-5 mm)的龈沟液中上述炎症介质的浓度。对照组由16名健康牙周组织组成。在所有患者中,用ELISA方法测定GCF中MMP-8和IL-1β的水平。

结果显示,牙周炎患者牙周组织深Ⅱ度和浅牙周组织中MMP-8和IL-1β的浓度明显高于正常人。侵袭性牙周炎(AP)或慢性牙周炎(CP)患者未观察到炎症介质的浓度差异。

原始出处:

Nędzi-Góra M, Górska R, et al., Concentration of MMP-8 and IL-1β in gingival crevicular fluid in patients with chronic and aggressive periodontitis. Cent Eur J Immunol. 2017;42(4):342-346. doi: 10.5114/ceji.2017.72824. Epub 2017 Dec 30.

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    2018-03-03 sunyl07
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    2018-03-03 rgjl
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  6. [GetPortalCommentsPageByObjectIdResponse(id=1686880, encodeId=459316868804a, content=<a href='/topic/show?id=1fc71035e1c1' target=_blank style='color:#2F92EE;'>#龈沟液#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103571, encryptionId=1fc71035e1c1, topicName=龈沟液)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=0fa428300788, createdName=ms8435843352634314, createdTime=Mon Jun 18 16:16:00 CST 2018, time=2018-06-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366294, encodeId=8f3413662940c, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Sat Mar 03 04:16:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1368645, encodeId=ded9136864568, content=<a href='/topic/show?id=0e30535657b' target=_blank style='color:#2F92EE;'>#慢性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=53565, encryptionId=0e30535657b, topicName=慢性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5c64275, createdName=piaojinhua, createdTime=Sat Mar 03 04:16:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423861, encodeId=68bb14238618e, content=<a href='/topic/show?id=66d29650ac' target=_blank style='color:#2F92EE;'>#IL-1β#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9650, encryptionId=66d29650ac, topicName=IL-1β)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7ea3859416, createdName=rgjl, createdTime=Sat Mar 03 04:16:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450780, encodeId=d23d1450e80d9, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Sat Mar 03 04:16:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1508206, encodeId=f57e1508206dc, content=<a href='/topic/show?id=8d4596248e' target=_blank style='color:#2F92EE;'>#IL-1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9624, encryptionId=8d4596248e, topicName=IL-1)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f6cf9946833, createdName=jjjiang0202, createdTime=Sat Mar 03 04:16:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536760, encodeId=48451536e60a5, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Sat Mar 03 04:16:00 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1544508, encodeId=56b4154450853, content=<a href='/topic/show?id=ac3d6549e75' target=_blank style='color:#2F92EE;'>#浓度#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65497, encryptionId=ac3d6549e75, topicName=浓度)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=16b213663040, createdName=12498974m55暂无昵称, createdTime=Sat Mar 03 04:16:00 CST 2018, time=2018-03-03, status=1, ipAttribution=)]
    2018-03-03 jjjiang0202
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