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JCEM：孕期和产后第一年生活方式干预有何影响？

2018-02-08 MedSci MedSci原创

孕期产后第一年生活方式
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众所周知有妊娠糖尿病（GDM）史的女性患2型糖尿病的风险高达7倍，而近日在JCEM上发表的一篇文章则评估了孕期和产后第一年的生活方式干预对高GDM风险妇女的血糖调节、体重保持和代谢特征的影响。

众所周知有妊娠糖尿病（GDM）史的女性患2型糖尿病的风险高达7倍，而近日在JCEM上发表的一篇文章则评估了孕期和产后第一年的生活方式干预对高GDM风险妇女的血糖调节、体重保持和代谢特征的影响。

研究人员在妊娠20周之前纳入269例之前有GDM和/或孕前BMI≥30kg / m2的妇女，分配为对照组或干预组。这项研究包括200受试者在产后6周和/或12个月进行研究访视。生活方式干预遵循北欧饮食的建议，每周至少推荐150分钟的适度运动。主要的测量结果是产后第一年葡萄糖调节受损（空腹血糖受损，葡萄糖耐量降低或2型糖尿病）的发生率。

研究结果显示在产后第一年，13.3％的对照组患者出现葡萄糖调节障碍，而干预组则有2.7％[调整年龄或OR 0.18（95％CI 0.05，0.65），P = 0.009]。产后12个月，体重保持、体力活动或饮食方面两组之间没有差异。

上述研表明孕期及产后第一年生活方式干预可以降低产后血糖调节受损的发生率。

原始出处：

Emilia Huvinen.et al. Effects of a Lifestyle Intervention During Pregnancy and First Postpartum Year - Findings from the RADIEL study. J Clin Endocrinol Metab. 2017.

本文系梅斯医学（MedSci）原创编译整理，转载需授权！



本文系梅斯医学（MedSci）原创编译整理，转载需授权！
本文系梅斯医学（MedSci）原创编译整理，转载需授权！
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    2018-12-09 achengzhao

    #JCE#

    0

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    2018-03-10 smallant2015

    #JCEM#

    0

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    2018-02-11 1e1c07bdm01(暂无匿称)

    好

    0

  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Feb 09 06:58:42 CST 2018, time=2018-02-09, status=1, ipAttribution=)]
    2018-02-11 jihuaijun1112

    学习学习学习

    0

  5. 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    2018-02-10 jyzxjiangqin

    孕期和产后弟一年生活方式.

    0

  6. 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    2018-02-09 swfzhanggui

    非常好.谢谢分享

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Fri Feb 09 09:20:37 CST 2018, time=2018-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286464, encodeId=299228646433, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Fri Feb 09 09:06:32 CST 2018, time=2018-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=286421, encodeId=e65828642173, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Feb 09 06:58:42 CST 2018, time=2018-02-09, status=1, ipAttribution=)]
    2018-02-09 飛歌

    学习了很有用不错

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Feb 09 06:58:42 CST 2018, time=2018-02-09, status=1, ipAttribution=)]
    2018-02-09 李东泽

    很好的学习材料.对临床和科研都有很大帮助作用.水滴石穿.不断积累.

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Feb 09 06:58:42 CST 2018, time=2018-02-09, status=1, ipAttribution=)]
    2018-02-09 龙胆草

    学习谢谢分享

    0

  10. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Fri Feb 09 06:58:42 CST 2018, time=2018-02-09, status=1, ipAttribution=)]
    2018-02-09 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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近日，一篇发表在国际杂志The FASEB Journal上的研究报告中，来自康奈尔大学的研究人员通过研究发现，当女性在孕期摄入足够水平的营养胆碱时，其后代将会获得更为持久的认知优势/益处，胆碱有多种功能，其在多种食物中都存在，比如蛋黄、瘦肉（红肉）、鱼肉、禽肉、豆类、坚果和十字花科蔬菜等，本文重点研究了胆碱在婴儿出生前大脑发育上所扮演的关键角色。

拿什么拯救你，我的孩子（母孕期感染乙肝、梅毒、艾滋病全攻略）

随着二胎政策的实施，哪怕没有老人照料孩子，哪怕每天累成狗，哪怕被大宝怨怼，也挡不住越来越多育龄女性迈入二胎大军，不为别的，只要想着小宝宝肉乎乎的小身子，软软糯糯的一声“妈妈”，瞬间融化。

Gut：孕期抗生素暴露增加新生儿极早性炎症性肠病风险

研究发现，孕期而非婴儿期抗生素暴露会增加新生儿极早发性炎症性肠病风险，孕期微生物种群变化可能是主要的影响因素

孕期增重与血压调节和糖脂代谢：现状及展望

2016年的统计数据显示，全球18岁以上成年超重人口的数量已超过19亿，其中6.5亿人为肥胖，占世界人口总数的13%。超重和肥胖的流行与久坐不动的生活方式和城市化相关的高脂肪、高能量饮食摄入过量有关。这种趋势在育龄期年轻女性中尤其明显。超重和肥胖是高血压的重要危险因素。

孕期用药知多少

怀孕期间，为了避免药物对胎宝宝的影响，准妈咪对于吃药这件事可谓是谨慎再谨慎，那么孕期生病到底该选择哪些相对安全的药物呢？

Clin Gastroenterol Hepatol:孕期接受生物疗法是否影响宝宝出生后对疫苗的反应？

炎症性肠病（IBD）通常在育龄女性中发病，而使用免疫调节剂对于生育、妊娠、婴儿结局的影响是临床医生和患者共同关注的部分。2018年1月，发表在《Clin Gastroenterol Hepatol》的一项由美国科学家进行的研究，考察了IBD孕妇接受生物疗法是否影响婴儿对疫苗的应答。